The focus of this research was to present a data article for analyzing the cost of displacing a drilling fluid during the drilling operation. The cost of conventional Spud, KCl and Pseudo Oil base (POBM) muds used in drilling oil and gas wells are compared with that of a Reversible Invert Emulsion Mud. The cost analysis is limited to three sections for optimum and effective Comparison.
View Article and Find Full Text PDFEffect of the dispersion method employed during the synthesis of carbon nanotube (CNT)/polysulfone-infused composite membranes on the quality and separation performance of the membranes during oil-water mixture separation is demonstrated. Carbon nanotube/polysulfone composite membranes containing 5% CNT and pure polysulfone membrane (with 0% CNT) were synthesized using phase inversion. Three CNT dispersion methods referred to as Method 1 (M1), Method 2 (M2), and Method 3 (M3) were used to disperse the CNTs.
View Article and Find Full Text PDFThe influence of different charging current densities, charging times and several structural designs on symmetric electrochemical capacitor (EC) performance, including capacitance, energy density and power density, has been investigated via modelling and simulation. Understanding the effects of different operating conditions and structural design variables on a capacitor's performance will guide in the optimal design and fabrication of high performance ECs. The operating conditions and design configurations examined were charging current density, charging times, electrode and electrolyte effective conductivity, electrode thickness and electrode porosity.
View Article and Find Full Text PDFThe purpose of this study was to explore the use of molecular bio-imaging systems and biomechanical dynamics to elucidate the fate of a nanocomposite hydrogel system prepared by merging FITC-labeled nanolipobubbles within a cross-linked hydrogel network. The nanocomposite hydrogel system was characterized by size distribution analysis and zeta potential as well as shears thinning behavior, elastic modulus (G'), viscous loss moduli (G"), TEM, and FTIR. In addition, molecular bio-imaging via Vevo ultrasound and Cell-viZio techniques evaluated the stability and distribution of the nanolipobubbles within the cross-linked hydrogel.
View Article and Find Full Text PDFSelf-discharge is known to have considerable adverse effects on the performance and application of electrochemical capacitors (ECs). Thus, obtaining an understanding of EC self-discharge mechanism(s) and subsequent derivation and solution of EC models, subject to a particular mechanism or combination of mechanisms during charging, discharging and storage of the device, is the only way to solve problems associated with EC self-discharge. In this review, we summarize recent progress with respect to EC self-discharge by considering the two basic types, electric double-layer capacitors (EDLC) and pseudocapacitors, and their hybrids with their respective charge storage mechanisms, distinguishable self-discharge mechanisms, charge redistribution and charge/energy loss during self-discharge.
View Article and Find Full Text PDFThis study reports the use of biocompatible and biodegradable polymers for the formulation and design of an implantable multipolymeric drug delivery device (MDDD) for the management of AIDS dementia complex (ADC), a debilitating condition affecting the cognitive, motor and behavioral systems in HIV+ individuals. A 3-factor Box-Behnken statistical design was employed for the optimization of nanoparticle and multipolymeric scaffold formulations. Fifteen formulations were generated using the Box-Behnken template, which were assessed for physicochemical and physicomechanical characterization.
View Article and Find Full Text PDFCashew apple juice (CAJ) is one of the feedstocks used for biofuel production and ethanol yield depends on the physical and chemical properties of the extracted juice. As far as can be ascertained, information on physical and chemical properties of South African cashew apple juice is limited in open literature. Therefore, this study provides information on the physical and chemical properties of the South African cashew apple juice.
View Article and Find Full Text PDFThis study investigates carbon nanotube (CNT) production from coal pyrolysis wherein the output gases are used in a chemical vapor deposition reactor. The carbon products are similar to those using commercial coal gas as feedstock, but coal is a relatively cheaper feedstock compared to high purity source gases. A Gibbs minimization model has been developed to predict the volume percentages of product gases from coal pyrolysis.
View Article and Find Full Text PDFPurpose: Nanomedicine explores and allows for the development of drug delivery devices with superior drug uptake, controlled release and fewer drug side-effects. This study explored the use of nanosystems to formulate an implantable drug delivery device capable of sustained zidovudine release over a prolonged period.
Methods: Pectin and alginate nanoparticles were prepared by applying a salting out and controlled gelification approach, respectively.
The purpose of this study was to design ligand-functionalized nanoliposomes that are proficient in providing effective intracellular delivery of an alkaloid drug (galantamine) into PC12 neuronal cells in response to managing Alzheimer's disease (AD). Ligand-functionalized nanoliposomes were produced and validated for their physicochemical properties, in silico molecular mechanics energy relationships, ex vivo cytotoxicity, peptide coupling efficiency (PCE), drug entrapment efficiency (DEE), drug release, fluorometry and confocal microscopy. Particle sizes of the nanoliposomes ranged from 127 nm to 165 nm (PdI=0.
View Article and Find Full Text PDFA carbon nanotube (CNT) integrated polymer composite membrane with a polyvinyl alcohol barrier layer has been prepared to separate oil from water for treatment of oil-containing waste water. The CNTs were synthesised using chemical vapour deposition, and a phase inversion method was employed for the blending of the CNTs in the polymer composite solution for casting of the membrane. Relative to the baseline polymer, an increase of 119% in the tensile strength, 77% in the Young's modulus and 258% in the toughness is seen for a concentration of 7.
View Article and Find Full Text PDFThe purpose of this study was to develop poly(lactic acid)-methacrylic acid copolymeric nanoparticles with the potential to serve as nanocarrier systems for methotrexate (MTX) used in the chemotherapy of primary central nervous system lymphoma (PCNSL). Nanoparticles were prepared by a double emulsion solvent evaporation technique employing a 3-Factor Box-Behnken experimental design strategy. Analysis of particle size, absolute zeta potential, polydispersity (Pdl), morphology, drug-loading capacity (DLC), structural transitions through FTIR spectroscopy, and drug release kinetics was undertaken.
View Article and Find Full Text PDFPurpose: To develop chelating ligand-bound nanoliposomes (NLPs) for the prevention and reversal of β-Amyloid (Aβ) aggregation associated with promoting neurotoxicity in Alzheimer disease (AD).
Methods: Four different chelating ligands (CuAc, EDTA, histidine and ZnAc) were surface-engineered onto NLPs using either covalent or non-covalent conjugation. Successful conjugation of chelating ligands onto the surface of NLPs was confirmed by characterization studies: SEM, TEM and FTIR analysis.
J Biomed Biotechnol
October 2012
Recently, interest in using bioethanol as an alternative to petroleum fuel has been escalating due to decrease in the availability of crude oil. The application of bioethanol in the motor-fuel industry can contribute to reduction in the use of fossil fuels and in turn to decreased carbon emissions and stress of the rapid decline in crude oil availability. Bioethanol production methods are numerous and vary with the types of feedstock used.
View Article and Find Full Text PDFThe new scientific innovation of engineering nanoparticles (NPs) at the atomic scale of 100 nm or less, has led to numerous novel and useful wide applications in electronics, chemicals, environmental protection, biological medicine. Manufacturers and consumers of the nanoparticles-related industrial products however, are likely to be exposed to these engineered nanomaterials which have various physical and chemical properties. These nanosize particles are likely to increase an unnecessary infinite toxicological effect on animals and environment, although their toxicological effects associated with human exposure are still unknown.
View Article and Find Full Text PDFCoagulation and flocculation treatment processes play a central role in the way wastewater effluents are managed. Their primary function is particle removal that can impart colour to a water source, create turbidity, and/or retain bacterial and viral organisms. This study was carried out to investigate whether carbon nanotubes (CNTs) can be used as heterogeneous coagulants and/or flocculants in the pretreatment of brewery wastewater.
View Article and Find Full Text PDFThe volume of industrial and domestic wastewater is increasing significantly year by year with the change in the lifestyle based on mass consumption and mass disposal brought about by the dramatic development of economies and industries. Therefore, effective advanced wastewater treatment is required because wastewater contains a variety of constituents such as particles, organic materials, and emulsion depending on the resource. However, residual chemicals that remain during the treatment of wastewaters form a variety of known and unknown by-products through reactions between the chemicals and some pollutants.
View Article and Find Full Text PDFThis study focused on the design, biometric simulation and optimization of an intracranial nano-enabled scaffold device (NESD) for the site-specific delivery of dopamine (DA) as a strategy to minimize the peripheral side-effects of conventional forms of Parkinson's disease therapy. The NESD was modulated through biometric simulation and computational prototyping to produce a binary crosslinked alginate scaffold embedding stable DA-loaded cellulose acetate phthalate (CAP) nanoparticles optimized in accordance with Box-Behnken statistical designs. The physicomechanical properties of the NESD were characterized and in vitro and in vivo release studies performed.
View Article and Find Full Text PDFThe purpose of this study was to develop a drug-loaded nanosystem that has the ability to achieve flexible yet rate-controlled release of model drug isoniazid (INH) employing either an aqueous or emulsion-based salting-out approach. Formulation conditions were aimed at reducing the polymeric size with subsequent rate-modulated INH release patterns from the polymeric nanosystem. The emulsion-based salted-out nanosystems had particle sizes ranging from 77-414 nm and a zeta potential of -24 mV.
View Article and Find Full Text PDFCassava (Manihot esculenta Crantz) is a known source of linamarin, but difficulties associated with its isolation have prevented it from being exploited as a major source. A batch adsorption process using activated carbon proved successful in its isolation, with ultrafiltration playing a pivotal role in its purification. Thirty-two minutes of contact time was required for 60 g of extract, yielding 1.
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