Publications by authors named "Sunkara B V Chowdary"
Article Synopsis
- Single-nucleotide variants (SNVs) are common genetic variations, and new methods for detecting them from single-cell DNA sequencing, like SCIΦ and scVILP, face scalability issues despite their accuracy.
- A new method called Phylovar improves upon existing techniques by efficiently handling large genomic datasets while outperforming SCIΦ in speed and providing more accurate results than non-phylogeny-aware methods like Monovar.
- Phylovar has been successfully applied to real biological datasets, detecting significant SNVs in both triple-negative breast cancer and neuron cells related to neurodegenerative diseases, and is available for public use on GitHub.
