Publications by authors named "Sunita Maria Christina De Sousa"
J Endocr Soc
September 2021
Article Synopsis
- Corticosteroid-binding globulin (CBG) is crucial for transporting cortisol in the body, binding about 90% of it in circulation.
- A new variant called "CBG Montevideo" causes a significant drop in CBG levels, leading to low cortisol in a 7-year-old boy and his mother, presenting symptoms like hypoglycemia and chronic fatigue.
- Unlike previous cases linked to CBG variants, this variant suggests CBG may play a special role in regulating glucose levels and communication between cortisol and the brain, despite normal free cortisol levels.
