Publications by Sunish Kadayil Sachith

Publications by authors named "Sunish Kadayil Sachith"

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Parental transmission effects of the IRF6 polymorphisms among Non-Syndromic Cleft Lip with or without cleft palate in Kerala case parent trios.

Reema Rose Alappat Sunish Kadayil Sachith Pulikkottil Raphael Varghese Puthucode V Narayanan Alex George

Arch Oral Biol

November 2024

Article Synopsis

This study aimed to investigate the role of IRF6 gene polymorphisms in individuals with Non-syndromic Orofacial Cleft (NSOFC) in Kerala.
The research involved analyzing DNA from 100 case-parent triads and specifically focused on the polymorphisms rs2235371 and rs7552506 using PCR and Sanger sequencing.
Results indicated a significant association between rs2235371 and NSOFC, particularly linked to paternal ancestry, while rs7552506 exhibited maternal linkage, suggesting IRF6 could be a risk factor for NSOFC in this population.

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Statistical optimization of thermostable alkaline protease from Bacillus cereus KM 05 using response surface methodology.

Devi Jayakumar Sunish Kadayil Sachith Vinod Kumar Nathan Kalappurakkal Saidu Muhammed Rishad

Biotechnol Lett

October 2021

Objectives: Proteases have gained great attention due to their enormous applications in food, tannery, detergent, photography and many other industries. Proteases rank third position in the production of enzymes. This paper targets to isolate a bacterium with high alkaline protease activity and optimization of its production conditions using Response Surface Methodology (RSM).