Publications by authors named "Sunil Manohar Keswani"
Article Synopsis
- Hypopigmentation from deep dermal burns lacks standardized treatment, making understanding its underlying molecular and cellular events crucial for potential therapies.
- Hematoxylin and Eosin (H&E) and Fontana Masson (FM) staining revealed significant structural and functional changes in post burn hypopigmented skin, confirmed by immunohistochemistry analysis of key cellular markers.
- A co-culture model of keratinocytes and melanocytes showed abnormal cellular interactions, reduced melanin production, and issues with cell proliferation, highlighting the need for further research to develop effective treatments for post burn hypopigmentation.
In India approximately 1 million people get burnt every year and most of them are from the lower or middle income strata. Therefore it is obligatory to find out an economic way of treatment for the affected populace. Since use of human skin allograft is the gold standard for the treatment of burn wound, in-house skin banking for a burn unit hospital is prerequisite to make the treatment procedure affordable.
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