Publications by authors named "Sunil Kayesth"
Article Synopsis
- Infections caused by the protozoan Giardia can be asymptomatic or lead to symptoms like diarrhea (non-bloody), abdominal cramps, bloating, flatulence, and weight loss, making it a significant health concern, especially for children under five.
- Giardia is the third leading cause of diarrhea and death in young children, following rotavirus and other infections, and is primarily treated with antimicrobial drugs like 5-nitroimidazole.
- The review suggests that individuals with weak immune systems are more susceptible to Giardia infections, but those in endemic areas may develop some resistance, indicating that future vaccination efforts, aided by advancements in nanoparticle technology and antigen research, could effectively mitigate this parasitic disease.
Precision and Advanced Nano-Phytopharmaceuticals for Therapeutic Applications.
Nanomaterials (Basel)
January 2022
Phytopharmaceuticals have been widely used globally since ancient times and acknowledged by healthcare professionals and patients for their superior therapeutic value and fewer side-effects compared to modern medicines. However, phytopharmaceuticals need a scientific and methodical approach to deliver their components and thereby improve patient compliance and treatment adherence. Dose reduction, improved bioavailability, receptor selective binding, and targeted delivery of phytopharmaceuticals can be likely achieved by molding them into specific nano-formulations.
View Article and Find Full Text PDFCurcuma longa rhizome extract and Curcumin reduce the adhesion of Acanthamoeba triangularis trophozoites and cysts in polystyrene plastic surface and contact lens.
Int J Parasitol Drugs Drug Resist
December 2020
Curcuma longa and Curcumin have been documented to have a wide spectrum of pharmacological effects, including anti-Acanthamoeba activity. Hence, this study sought to explore the anti-adhesion activity of C. longa extract and Curcumin against Acanthamoeba triangularis trophozoites and cysts in plastic and contact lenses.
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