Free antibiotic and vaccination programmes in community pharmacies of Miami-Dade County, FL, USA.

Objectives: Some community pharmacies provide prescribed oral antibiotics for free to incentivize customers. This can influence prescribing practices and may increase inappropriate antibiotic use. Thus, pleas to incorporate education and/or vaccinations into these initiatives have been made by the CDC and IDSA.

A run-based procedure to identify time-lagged gene clusters in microarray experiments.

Motivation: The analysis of gene-expression data obtained from microarray experiments can be useful to identify regulatory relationship between genes. Genes with a common functional role have similar expression patterns across different microarray experiments. These similar expression patterns are perhaps due to co-regulation of genes in the same functional group.

Identification of hair cycle-associated genes from time-course gene expression profile using fractal analysis.

Microarray technology permits one to monitor thousands of processes going on inside the cell. This tool has been used to study gene expression profiles associated with the hair-growth cycle. We provide a novel method called the fractal analysis method to identify hair-growth cycle associated genes from time course gene expression profiles.

A nonparametric likelihood ratio test to identify differentially expressed genes from microarray data.

Microarray experiments contribute significantly to the progress in disease treatment by enabling a precise and early diagnosis. One of the major objectives of microarray experiments is to identify differentially expressed genes under various conditions. The statistical methods currently used to analyse microarray data are inadequate, mainly due to the lack of understanding of the distribution of microarray data.

Fractal binding and dissociation kinetics of heart-related compounds on biosensor surfaces.

A fractal analysis is presented for the binding and dissociation of different heart-related compounds in solution to receptors immobilized on biosensor surfaces. The data analyzed include LCAT (lecithin cholesterol acyl transferase) concentrations in solution to egg white apoA-I rHDL immobilized on a biosensor chip surface (1), native, mildly oxidized, and strongly oxidized LDL in solution to a heparin-modified Au-surface of a surface plasmon resonance (SPR) biosensor (2), and TRITC-labeled HDL in solution to a bare optical fiber surface (3). Single-and dual-fractal models were used to fit the data.