Comparative Analysis of Coumarin Profiles in Different Parts of and Their Aldo-Keto Reductase Inhibitory Activities.

(Umbelliferae) is widely distributed throughout Southeast Asian countries. The root of this plant is used in traditional medicine to treat colds and pain, whereas the young leaves are considered an edible vegetable. In this study, the differences in coumarin profiles for different parts of including the flowers, roots, leaves, and stems were compared using ultra-performance liquid chromatography time-of-flight mass spectrometry.

Absolute Quantification of Isoflavones in the Flowers of by qHNMR.

(Willd.) Ohwi. is a widely used medicinal plant in Korea, China, and Japan.

Metabolite Profiling and Dipeptidyl Peptidase IV Inhibitory Activity of Cultivars in Different Mutations.

species have been developed to produce cultivars of various floral colors and sizes and are also used in traditional medicine. To identify and evaluate mutant cultivars of . and .

9‑Hydroxy‑isoegomaketone inhibits LPS‑induced NO and inflammatory cytokine production in RAW264.7 cells.

Isoegomaketone (IK) is a known component of that reportedly exhibits anti‑inflammatory, anti‑cancer and anti‑allergic properties. A novel compound known as 9‑HIK has been isolated from the extract of a radiation mutant var. using supercritical carbon dioxide.

Constituents of Flower and Their Dipeptidyl Peptidase IV Inhibitory Effects.

A new polyacetylene glycoside, (5)-6-tetradecene-8,10,12-triyne-1-ol-5---glucoside (), was isolated from the flower of (Compositae), together with two known compounds, bidenoside C () and (3,4)-5-trideca-1,5-dien-7,9,11-triyne-3,4-diol-4---glucopyranoside (), which were found in species for the first time. The other known compounds, lanceoletin (), 3,2'-dihydroxy-4-3'-dimethoxychalcone-4'-glucoside (), 4-methoxylanceoletin (), lanceolin (), leptosidin (), (2)-8-methoxybutin (), luteolin () and quercetin (), were isolated in this study and reported previously from this plant. The structure of was elucidated by analyzing one-dimensional and two-dimensional nuclear magnetic resonance and high resolution-electrospray ionization-mass spectrometry data.

Constituents of the leaves and twigs of Elaeagnus umbellata and their proliferative effects on human keratinocyte HaCaT cells.

Bioassay-guided fractionation of an extract of leaves and twigs of Elaeagnus umbellata led to the isolation of a serotonin derivative, N-[2-(5-hydroxyl-1H-indol-3-yl)ethyl]-butanamide (1), along with six flavonoid glycosides, kaempferol-3-O-β-d-xylopyranosyl(1 → 2)-β-d-galactopyranoside-7-O-α-l-rhamnopyranoside (2), kaempferol-3-O-β-d-galactopyranoside-7-O-α-l-rhamnopyranoside (3), kaempferol-3-O-α-l-rhamnopyranosyl(1 → 6)-β-d-galactopyranoside-7-O-α-l-rhamnopyranoside (4), kaempferol-3-O-β-d-xylopyranosyl(1 → 2)-β-d-galactopyranoside (5), kaempferol-3-O-rutinoside (6), and kaempferol-3-O-β-d-glucopyranosyl(1 → 2)-β-d-galactopyranoside-7-O-α-l-rhamnopyranoside (7). Their structures were elucidated using 1D/2D nuclear magnetic resonance spectroscopy and mass spectrometry. Compounds 1-6 were evaluated for their proliferative effects on HaCaT keratinocytes; 1-5 promoted keratinocyte proliferation dose dependently.

Preparative Separation of Three Monoterpenes from var. Using Centrifugal Partition Chromatography.

Three monoterpenes, namely, 9-hydroxy isoegomaketone (), isoegomaketone (), and perilla ketone (), were successfully separated from the supercritical carbon dioxide (SC-CO) extract of the leaves of var. (cv. Antisperill; Lamiaceae) by centrifugal partition chromatography (CPC).