Publications by authors named "Sunhyun Ahn"
Gender differences in hepatitis A seropositivity rates according to the Republic of Korea's vaccination policy.
Osong Public Health Res Perspect
April 2024
Article Synopsis
- - The study analyzed anti-hepatitis A virus (HAV) antibody levels from over 1.3 million tests conducted between 2012 and 2022, focusing on age and gender differences in seropositivity rates.
- - Results showed a U-shaped pattern, with lower seropositivity rates for those aged 20 to 39, but higher rates for younger and older individuals, while the rates gradually declined for those aged 35 and older.
- - A significant gender gap was observed, especially in men aged 20 to 29, likely influenced by military enlistment, highlighting the need for targeted vaccination policies for adults to reduce severe infection risks.
Aims: Lipids are central in the development of cardiovascular disease, and the present study aimed to characterize variation in lipid profiles across different countries to improve understanding of cardiovascular risk and opportunities for risk-reducing interventions.
Methods And Results: This first collaborative report of the Global Diagnostics Network (GDN) evaluated lipid distributions from nine laboratory organizations providing clinical laboratory testing in 17 countries on five continents. This cross-sectional study assessed aggregated lipid results from patients aged 20-89 years, tested at GDN laboratories, from 2018 through 2020.
To achieve the measurement reliability of amino acids used as diagnostic markers in clinical fields, establishing a reference measurement system is required, in which certified reference materials (CRMs) are an essential step in the hierarchy of measurement traceability. This study describes the development of dried blood spot (DBS) CRMs for amino acid analysis with complete measurement traceability to the International System of Units (SI). Six essential amino acids─proline, valine, isoleucine, leucine, phenylalanine, and tyrosine─were analyzed using isotope-dilution liquid chromatography-mass spectrometry (ID-MS).
View Article and Find Full Text PDFBackground: Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is increasingly used for immunosuppressive drug tests. However, most LC-MS/MS tests are laboratory-developed and their agreement is unknown in different Korean laboratories. This interlaboratory comparison study evaluated test reproducibility and identified potential error sources.
View Article and Find Full Text PDFContext: The Samsung LABGEO(HC10) Hematology Analyzer (LABGEO(HC10)) is a recently developed automated hematology analyzer that uses impedance technologies. The analyzer provides 18 parameters including 3-part differential at a maximum rate of 80 samples per hour.
Objective: To evaluate the performance of the LABGEO(HC10).
Article Synopsis
- Acute promyelocytic leukemia (APL) is a serious condition that needs urgent diagnosis and treatment, which can be achieved through various methods like blood tests and genetic analysis.
- A study of 48 APL patients in Korea found wide variations in white blood cell and platelet counts, with most patients showing high levels of certain blood markers, indicating a severe condition.
- The key genetic marker for APL was detected in all patients, highlighting the need for quicker diagnostic techniques to facilitate timely treatment.*