The Dipeptide Gly-Pro (GP), Derived from , Exhibits Potent Antifibrotic Effects by Regulating the TGF-β1-ATF4-Serine/Glycine Biosynthesis Pathway.

TGF-β1, a key fibrotic cytokine, enhances both the expression and translocation of the activating transcriptional factor 4 (ATF4) and activates the serine/glycine biosynthesis pathway, which is crucial for augmenting collagen production. Targeting the TGF-β1-ATF4-serine/glycine biosynthesis pathway might offer a promising therapeutic approach for fibrotic diseases. In this study, we aimed to identify a proline-containing dipeptide in plant cells that modulates collagen synthesis.

Single Nucleotide Polymorphism Assay for Genetic Identification of Lophophora williamsii.

Lophophora is a member of the Cactaceae family, which contains two species: Lophophora williamsii and L. diffusa. Lophophora williamsii is an illegal plant containing mescaline, a hallucinogenic alkaloid.

p-wave resonant bose gas: a finite-momentum spinor superfluid.

We show that a degenerate gas of two-species bosonic atoms interacting through a p-wave Feshbach resonance (as realized in, e.g., a (85)Rb -- (87)Rb mixture) exhibits a finite-momentum atomic-molecular superfluid (AMSF), sandwiched by a molecular p-wave (orbital spinor) superfluid and by an s-wave atomic superfluid at large negative and positive detunings, respectively.