Publications by authors named "Sunghee Kuk"
Occurrence of metabolic diseases associated with antipsychotic use among Korean patients with schizophrenia.
Int J Clin Pharmacol Ther
April 2021
Article Synopsis
- * It finds that both typical and atypical antipsychotics increase the risk of metabolic diseases, particularly highlighting clozapine and quetiapine as having notable associations with these health issues.
- * The authors conclude that there is a significant link between antipsychotic use and metabolic diseases, emphasizing the need for further research to confirm these findings and consider dosages.
In meta-analysis, hypothesis testing is one of the commonly used approaches for assessing whether heterogeneity exists in effects between studies. The literature concluded that the Q-statistic is clearly the best choice and criticized the performance of the likelihood ratio test in terms of the type I error control and power. However, all the criticism for the likelihood ratio test is based on the use of a mixture of two chi-square distributions with 0 and 1 degrees of freedom, which is justified only asymptotically.
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