Myogenic autoregulation in bone marrow arterioles and in vivo intramedullary pressure in femora of conscious, female Long Evans rats.

Objectives: The ability to regulate skeletal blood flow is critical for the maintenance of bone. The myogenic response is essential for regulating tissue blood flow. Myogenic responsiveness in bone marrow arterioles has not yet been determined.

An Implanted Magnetic Microfluidic Pump for In Vivo Bone Remodeling Applications.

Modulations of fluid flow inside the bone intramedullary cavity has been found to stimulate bone cellular activities and augment bone growth. However, study on the efficacy of the fluid modulation has been limited to external syringe pumps connected to the bone intramedullary cavity through the skin tubing. We report an implantable magnetic microfluidic pump which is suitable for in vivo studies in rodents.