Acute and chronic effects of the antifouling booster biocide Irgarol 1051 on the water flea Moina macrocopa revealed by multi-biomarker determination.

Irgarol 1051 is an herbicide extensively utilized in antifouling paint due to its ability to inhibit photosynthesis. Irgarol and its photodegradation products are highly persistent in waters and sediments, although they are present in low concentrations. However, our understanding of the harmful effects of Irgarol on non-target organisms remains limited.

Effects of Melatonin, GM-CSF, IGF-1, and LIF in Culture Media on Embryonic Development: Potential Benefits of Individualization.

The implantation of good-quality embryos to the receptive endometrium is essential for successful live birth through in vitro fertilization (IVF). The higher the quality of embryos, the higher the live birth rate per cycle, and so efforts have been made to obtain as many high-quality embryos as possible after fertilization. In addition to an effective controlled ovarian stimulation process to obtain high-quality embryos, the composition of the embryo culture medium in direct contact with embryos in vitro is also important.

Pharmacokinetic Comparison of Ginsenosides between Fermented and Non-Fermented Red Ginseng in Healthy Volunteers.

Fermentation of red ginseng (RG) produces fermented red ginseng (FRG), thereby increasing the relative amount of downstream ginsenosides, including compound Y (CY), F2, Rh2, compound K (CK), compound O, protopanaxadiol (PPD), and protopanaxatriol (PPT). These downstream ginsenosides have beneficial pharmacological effects, and are easily absorbed by the human body. Based on these expectations, a randomized, single-dose, two-period, crossover clinical trial was planned to compare the pharmacokinetic characteristics of seven types (Rb1, CY, F2, CK, Rh2, PPD, and PPT) of ginsenoside components after FRG and RG administration.

Methane Sulfonation via a Free-Radical Mechanism by Trifluoroacetylsulfuric Acid.

Using trifluoroacetyl sulfuric acid (TFAOSOH), we discovered a new methane activation method and revealed its radical pathway under mild conditions. Upon the addition of a radical initiator with methane, the crude solution of TFAOSOH developed the methyltrifluoroacetylsulfate radical ((TFAO)CHS(OH)O•). The resulting (TFAO)CHS(OH)O• behaved as a critical radical propagator for carbon-hydrogen bond activation, culminating in successful methane sulfonation.

Long-term exposure to antifouling biocide chlorothalonil modulates immunity and biochemical and antioxidant parameters in the blood of olive flounder.

In this study, the potential effects of 30-day exposure to environmentally relevant concentrations of chlorothalonil (0, 5, 10, and 20 μg L) were tested in the blood of the economically important olive flounder, Paralichthys olivaceus, using biochemical endpoints. Significant decreases in the enzymatic activities of immunity markers, alternative complements, and lysozymes were detected in the fish exposed to 10 or 20 μg L of chlorothalonil at day 20 or 30. The total immunoglobulin content was lowered in response to 20 μg L chlorothalonil at day 10 and 20, even when later exposed to 5 μg L at day 30.

ATHB17 is a positive regulator of abscisic acid response during early seedling growth.

We performed activation tagging screen to isolate abscisic acid (ABA) response mutants. One of the mutants, designated ahs10 (ABA-hypersensitive 10), exhibited ABA-hypersensitive phenotypes. TAIL-PCR analysis of the mutant revealed that T-DNA was inserted in the promoter region of the Arabidopsis gene, At2g01430, which encodes a homeodomain-leucine zipper protein ATHB17.

Vitamin A status of 20- to 59-year-old adults living in Seoul and the metropolitan area, Korea.

Dietary intakes and plasma concentrations of retinol and carotenoids were estimated in assessing the vitamin A status of Korean adults living in Seoul and the metropolitan area. Three consecutive 24-h food recalls were collected from 106 healthy subjects (33 males and 73 females) aged 20-59 years. Fasting blood samples of the subjects were obtained and plasma retinol and carotenoids were analyzed.