Publications by authors named "SungWoo Park"

Fiber-reinforced polymers (FRPs), which are resistant to corrosion, are used as reinforcement material for concrete. However, the flexural behavior of concrete members reinforced with FRPs can vary depending on the properties of FRPs. In this study, the flexural behavior of one-way concrete slab specimens reinforced with a new grid-type carbon-fiber-reinforced polymer (CFRP) (carbon grid) manufactured by bonding pultruded CFRP strands to an adhesive was investigated.

View Article and Find Full Text PDF

Background: Molecular and transcription factor subtyping were recently introduced to identify patients with unique clinical features in small cell lung cancer (SCLC). However, its prognostic relevance is yet to be established. This study aims to investigate the clinical implications and prognostic significance of transcription factor subtyping in SCLC using immunohistochemistry.

View Article and Find Full Text PDF
Article Synopsis
  • Two Typhimurium strains, JOL 912 and JOL 1800, were engineered from the wild-type strain by deleting specific genes, which weakened their ability to survive inside host cells and gave them distinct immune responses.
  • The study examined how these strains reacted to different stress factors like temperature and acidity, finding that cold stress slightly increased their invasion abilities, while their entry mechanisms stayed consistent across cell types.
  • JOL 912 triggered a strong immune response, activating important immune factors, whereas JOL 1800 had a minimal response, and the gene deletions affected cell cycle progression and apoptosis in infected cells.
View Article and Find Full Text PDF

All-solid-state lithium batteries, including sulfide electrolytes and nickel-rich layered oxide cathode materials, promise safer electrochemical energy storage with high gravimetric and volumetric densities. However, the poor electrical conductivity of the active material results in the requirement for additional conducive additives, which tend to react negatively with the sulfide electrolyte. The fundamental scientific principle uncovered through this work is simple and suggests that the electrical network benefits associated with the introduction of short-length carbons will eventually be overpowered by the increase in bulk resistance associated with their instability in the sulfide electrolyte.

View Article and Find Full Text PDF

Early diagnosis of pregnancy is directly related to cost-effective livestock production. We produced a rat monoclonal antibody (mAb) against synthesized porcine early pregnancy factor (pEPF) using conventional hybridoma technology and used it as a tool for the detection of early pregnancy in Duroc sows. The rat pEPF-mAb showed reactivity to uterine tissues of pregnant sows 20 or 30 days post-mating (day 0 defined as the day of mating) and non-pregnant sows (confirmed signs of estrus) in western blotting.

View Article and Find Full Text PDF

Background: Systemic inflammation is believed to contribute to small cell lung cancer (SCLC) progression, but the underlying relationship remains unclear. Lipocalin-2, a potential biomarker of inflammation, has been implicated in various cancers but its prognostic value in SCLC is underexplored.

Methods: We retrospectively analyzed 191 patients with SCLC (72 with limited-stage [LD] and 119 with extensive-stage) treated using platinum-based chemotherapy.

View Article and Find Full Text PDF

Muscle strength assessments are vital in rehabilitation, orthopedics, and sports medicine. However, current methods used in clinical settings, such as manual muscle testing and hand-held dynamometers, often lack reliability, and isokinetic dynamometers (IKD), while reliable, are not easily portable. The aim of this study was to design and validate a wearable dynamometry system with high accessibility, accuracy, and reliability, and to validate the device.

View Article and Find Full Text PDF
Article Synopsis
  • Myoinhibitory peptides (MIPs) play important roles in various physiological functions in invertebrates, but their signaling systems have not been fully studied in mollusks.
  • In this study, researchers identified eight distinct MIPs in the Pacific abalone, Haliotis discus hannai, and a functional receptor (Hdh-MIPR) that interacts with these peptides.
  • The findings showed that Hdh-MIPs can delay larval metamorphosis while promoting spawning behavior, indicating a unique function of MIPs in invertebrate biology.
View Article and Find Full Text PDF
Article Synopsis
  • Patient isolation units (PIUs) are effective for infection control, but optimizing their design typically requires extensive computational resources, which this study aims to address using data-driven models.
  • The study used computational fluid dynamics (CFD) to examine how various PIU settings and room conditions impact ventilation and isolation, focusing on airflow patterns and particle dispersion from coughing.
  • Key findings indicate that while physical isolation alone isn't enough to stop particle spread, the addition of a fan filter unit (FFU) significantly improves isolation performance, with its positioning being the most crucial factor influencing PIU effectiveness.
View Article and Find Full Text PDF
Article Synopsis
  • Idiopathic pulmonary fibrosis (IPF) is marked by abnormal lung tissue remodeling and surplus extracellular matrix proteins, with increased levels of ornithine aminotransferase (OAT) found in patients.
  • Research indicates that OAT plays a significant role in IPF's progression, influencing extracellular matrix production and mitochondrial reactive oxygen species (ROS) generation in lung fibroblasts.
  • Inhibiting OAT showed promise in reducing lung injury and fibrosis in mice treated with bleomycin, suggesting that targeting OAT could be a potential therapeutic approach for patients with fibrotic lung diseases like IPF.
View Article and Find Full Text PDF

Background: is the causative agent of proliferative enteropathy and is associated with several outbreaks, causing substantial economic loss to the porcine industry.

Objectives: In this study, we focused on demonstrating the protective effect in the mouse model through the immunological bases of two vaccine strains against porcine proliferative enteritis.

Methods: We used live-attenuated Typhimurium (ST) secreting two selected immunogenic LI antigens ( autotransporter A epitopes and flagellin [FliC]-peptidoglycan-associated lipoprotein-FliC) as the vaccine carrier.

View Article and Find Full Text PDF
Article Synopsis
  • The study compared the effectiveness and safety of two treatments for metastatic hormone-sensitive prostate cancer (mHSPC): androgen-deprivation therapy (ADT) combined with abiraterone/prednisone versus ADT combined with docetaxel.
  • It analyzed data from 928 patients in South Korea, specifically focusing on 122 patients who received either treatment, assessing various factors like demographic characteristics, cancer status, and treatment outcomes.
  • Results showed that the ADT+abiraterone/prednisone group had a significantly lower rate of prostate-specific antigen (PSA) progression and a lower rate of treatment discontinuation compared to the ADT+docetaxel group, indicating it may be more effective, although further research is
View Article and Find Full Text PDF

Monitoring ankle strength is crucial for assessing daily activities, functional ability, and preventing lower extremity injuries. However, the current methods for measuring ankle strength are often unreliable or not easily portable to be used in clinical settings. Therefore, this study proposes a portable dynamometer with high reliability capable of measuring ankle dorsiflexion and plantar flexion.

View Article and Find Full Text PDF

Sulfide electrolyte all-solid-state lithium-ion batteries (ASSLBs) that have inherently nonflammable properties have improved greatly over the past decade. However, determining both the stable and functional electrode components to pair with these solid electrolytes requires significant investigation. Solid electrolyte comprises 20-40% of the composite cathode electrode, which improves the ionic conductivity.

View Article and Find Full Text PDF

Background: Although the prognostic value of the Controlling Nutritional Status (CONUT) score in diffuse large B-cell lymphoma (DLBCL) has been reported in several previous studies, its clinical relevance for the presence of sarcopenia has not been assessed.

Methods: In this study, 305 DLBCL patients were reviewed. They were categorized into normal/mild (n = 219) and moderate/severe (n = 86) CONUT groups.

View Article and Find Full Text PDF

This study quantified the spatial exploration of 13 infants born very and extremely preterm (PT) at 4 months corrected age as they learned that moving their feet vertically to cross a virtual threshold activated an infant kick-activated mobile and compared results to 15 infants born full-term (FT) from a previously published study. Spatial exploration was quantified using two general spatial exploration variables (exploration volume, exploration path), two task-specific spatial variables (duration of time in the task-specific region of interest, vertical variance of kicks), and one non-task-specific spatial variable (horizontal variance of kicks). The infants born PT, similar to FT, increased their general spatial exploration and duration in the region of interest and did not change the vertical and horizontal variances of kicks.

View Article and Find Full Text PDF

The membrane process has a limit to the decay of various pollutants in water. To improve the problem, the roles of backwashing media and titanium dioxide (TiO) photocatalyst-immobilized-polyethersulfone (PES) beads' concentration were investigated in a combined system of tubular alumina MF and the PES beads for advanced drinking water treatment. The space between the outside of the MF membrane and the module inside was filled with the PES beads.

View Article and Find Full Text PDF
Article Synopsis
  • A study aimed to optimize prostate biopsy indications by combining prostate health index density (PHID) with multiparametric MRI (mpMRI) to improve detection of clinically significant prostate cancer (csPCa).
  • The study analyzed data from 521 biopsies and found that using PHID alongside mpMRI resulted in the highest predictive accuracy for csPCa, allowing for a significant reduction in unnecessary biopsies.
  • Specifically, a PHID cutoff of 0.75 in men with PI-RADS 3 lesions led to a 100% negative predictive value, meaning no csPCa was missed while potentially avoiding half of the biopsies in this group.
View Article and Find Full Text PDF

Background: Mixed-phenotype acute leukemia (MPAL) is characterized by acute undifferentiated leukemia with blasts co-expressing myeloid and lymphoid antigens. However, consensus regarding the ideal management strategy for MPAL is yet to be established, owing to its rarity.

Case Summary: A 55-year-old male was diagnosed with T/myeloid MPAL.

View Article and Find Full Text PDF

Muscle strength assessment is important in predicting clinical and functional outcomes in many disorders. Manual muscle testing, although commonly used, offers suboptimal accuracy and reliability. Isokinetic dynamometers (IKDs) have excellent accuracy and reliability; but are bulky and expensive, offering limited accessibility.

View Article and Find Full Text PDF

Background: Individualized, targeted, and intense training is the hallmark of successful gait rehabilitation in people post-stroke. Specifically, increasing use of the impaired ankle to increase propulsion during the stance phase of gait has been linked to higher walking speeds and symmetry. Conventional progressive resistance training is one method used for individualized and intense rehabilitation, but often fails to target paretic ankle plantarflexion during walking.

View Article and Find Full Text PDF

Purpose: To evaluate the impact of paired transrectal ultrasonography (TRUS) findings of index lesions identified by multiparametric magnetic resonance imaging (mpMRI) on the detection rate of clinically significant prostate cancer (csPCa, Gleason score ≥7) during MRI/US fusion-targeted biopsies.

Materials And Methods: From 2019 to 2021, TRUS findings of paired index lesions were prospectively collected from MRI/US cognitive (cTB, n=299) or program-assisted (pTB, n=294) fusion-targeted biopsies. csPCa detection rates according to the presence of a paired hypoechoic lesion (HoEL) and predictive factors for csPCa detection by targeted biopsy were evaluated.

View Article and Find Full Text PDF
Article Synopsis
  • Proper lipid metabolism is essential for the function of alveolar epithelial cells (AECs), and excessive AEC death contributes to idiopathic pulmonary fibrosis (IPF).
  • Research shows that the enzyme fatty acid synthase (FASN) is downregulated in the lungs of IPF patients, and its overexpression can protect AECs from death caused by bleomycin.
  • Enhancing FASN levels may improve mitochondrial function and reduce lung inflammation and fibrosis, presenting a potential therapeutic avenue for IPF treatments.
View Article and Find Full Text PDF