The effect of synthetic ceramide analogues on gastritis and esophagitis in rats.

The effects of ceremide analogues on esophagitis and gastritis in rats were examined. Gastritis induced by indomethacin was significantly reduced after CY3325 and CY3723 treatment, whereas other analogues had no effect. The amount of malondialdehyde in gastritis was significantly reduced by CY3325 or CY 3723.

Relaxation effect of synthetic ceramide analogues in cat esophageal smooth muscle cells.

Ceramide has emerged as a novel second messenger for intracellular signalling. It is produced from sphingomyelin and is involved in the control of cell differntiation, proliferation, and apoptosis. C(2)-ceramide, short chain ceramide, plays a role in mediating contraction of cat esophageal smooth muscle cells.

Effect of hydrogen peroxide on VIP-induced relaxation of the cat lower esophageal sphincter.

We investigated the effects of hydrogen peroxide (H2O2) on relaxation of the cat lower esophageal sphincter (LES). Vasoactive intestinal peptide (VIP) caused dose-dependent relaxation of LES, and H2O2 reduced VIP-induced relaxation. Relaxation was also attenuated by pertussis toxin (PTX), indicating a Gi/o component.

[Effects of telephone intervention as supportive nursing on self-care practices and qualify of life for gynecological cancer patients under chemotherapy].

Purpose: The effects of telephone intervention on self-care practices and quality of life for gynecological cancer patients under chemotherapy was investigated.

Methods: A non-equivalent control group pre-test post-test quasi-experimental design was used. The subjects were women cancer patients who had received less than two chemotherapy sessions at C university hospital of Chonnam province(26 in the experimental group: 25 in the control group).

[Effects of educational program of manual lymph massage on the arm functioning and the quality of life in breast cancer patients].

Purpose: The purpose of this study was to determine the effect of EPMLM (educational program of manual lymph massage) on the arm functioning and QOL (quality of life) in breast cancer patients with lymphedema.

Method: Subjects in the experimental group (n=20) participated in EPMLM for 6 weeks from June to July, 2005. The EPMLM consisted of training of lymph massage for 2 weeks and encourage and support of self-care using lymph massage for 4 weeks.

[Effects of a closed endotracheal suction system on oxygen saturation, ventilator-associated pneumonia, and nursing efficacy].

Purpose: The purpose of this study was to examine the effects of a closed endotracheal suction system(CES) on oxygen saturation, ventilator associated pneumonia(VAP), and nursing efficacy in mechanically ventilated patients.

Method: This study was conducted in the intensive care unit of a University Hospital in Gwangju City. Data was collected from July to October, 2003.