Hypopituitarism Presenting as Adrenal Insufficiency and Hypothyroidism in a Patient with Wilson's Disease: a Case Report.

Wilson's disease typically presents symptoms associated with liver damage or neuropsychiatric disturbances, while endocrinologic abnormalities are rare. We report an unprecedented case of hypopituitarism in a patient with Wilson's disease. A 40-year-old woman presented with depression, general weakness and anorexia.

Amine-functionalized polyglycidyl methacrylate microsphere as a unified template for the synthesis of gold nanoparticles and single-crystal gold plates.

Polyglycidyl methacrylate (PGMA) microspheres, crosslinked and surface-functionalized by amine, can be used as a solid-state template for the synthesis of gold (Au) crystals in the forms of either nanoparticles (NPs) or plates. It is discovered that the polymer microsphere acts as an internal template to cultivate Au NPs inside the microsphere or an external template to generate the single-crystal plates depending on the critical concentration (Ccr ) of gold ions. The ion-dipole interaction and the structure-dependent solubility of gold induce two distinct gold nanostructures in the presence of the functionalized polymer microspheres.