Bcl-XL prevents serum deprivation-induced oxidative stress mediated by Romo1.

B-cell lymphoma-extra large (Bcl-XL) has been known to suppress serum deprivation-induced cell death, while reactive oxygen species modulator 1 (Romo1) is responsible for a serum deprivation-induced increase in reactive oxygen species (ROS). Therefore, we investigated whether Bcl-XL expression could inhibit the serum deprivation-induced increase in ROS and cell death, which are mediated by Romo1. We found that Bcl-XL expression effectively blocked serum deprivation- and Romo1-triggered ROS generation.

Clinical and histologic analysis of the stability of microimplants with immediate orthodontic loading in dogs.

Introduction: The aims of this study were to evaluate the stability of machined microimplant anchorage after immediate orthodontic loading in dogs and to ascertain clinical and histologic features.

Methods: Sixty microimplants were placed in the buccal sides of the maxillae and mandibles of 4 dogs, including the interradicular area. Superelastic nickel-titanium coil springs were activated between 24 pairs of reciprocally loaded implants, producing a force of 200 g, and the remaining 12 unloaded implants served as controls.

Mitochondrial reactive oxygen species originating from Romo1 exert an important role in normal cell cycle progression by regulating p27(Kip1) expression.

Reactive oxygen species (ROS) steady-state levels are required for entry into the S phase of the cell cycle in normal cells, as well as in tumour cells. However, the contribution of mitochondrial ROS to normal cell proliferation has not been well investigated thus far. A previous report showed that Romo1 was responsible for the high ROS levels in tumour cells.

Dicyanopyrazine-linked porphyrin Langmuir-Blodgett films.

We investigated the influence of arachidic acid/cadmium dication (AA/Cd(2+)) as a transfer promoter for the deposition of dicyanopyrazine-linked porphyrin (2-DCPP) Langmuir-Blodgett (LB) films on both hydrophobic and hydrophilic substrates. In the case of LB deposition on a hydrophilic substrate, the presence of AA/Cd(2+) does not improve 2-DCPP LB deposition. The poor transfer in the case of the hydrophilic surface is believed to be due to 2-DCPP not wetting the surface during the down-stroke deposition, and this is not improved by the transfer agent.

Ricinus communis contains an acyl-CoA synthetase that preferentially activates ricinoleate to its CoA thioester.

As part of our effort to identify enzymes that are critical for producing large amounts of ricinoleate in castor oil, we have isolated three cDNAs encoding acyl-CoA synthetase (ACS) in the castor plant. Analysis of the cDNA sequences reveals that two of them, designated RcACS 2 and RcACS 4, contain complete coding regions corresponding to 694 and 690 amino acids, respectively. The third cDNA, RcACS 1, encodes a truncated gene sequence.

Mapping of putative quantitative trait loci controlling the total oligosaccharide and sucrose content of Glycine max seeds.

Although oligosaccharides and sucrose are very important nutritional components of soybean seeds, little information is available about inheritance of oligosaccharide and sucrose content. The objective of this study was to identify quantitative trait loci (QTLs) that determine the oligosaccharide and sucrose content of soybean. The 117 F(2:10) recombinant inbred lines developed from a cross of "Keunolkong" and "Shinpaldalkong" were used.