Neutrophil-lymphocyte ratio as a valuable prognostic marker in idiopathic sudden sensorineural hearing loss.

Neutrophil-to-lymphocyte ratio (NLR) has emerged as a marker for degree of inflammation. Inflammation has been regarded as one of the causes of idiopathic sudden sensorineural hearing loss. This study investigated the potential association between neutrophil-to-lymphocyte ratio (NLR) and prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).

Expression of aquaporins in inner ear disease.

The inner ear is responsible for hearing and balance and consists of a membranous labyrinth within a bony labyrinth. The balance structure is divided into the otolith organ that recognizes linear acceleration and the semicircular canal that is responsible for rotational movement. The cochlea is the hearing organ.

The Relationship between Age-Related Hearing Loss and Cognitive Disorder.

Background: Although the rates of occurrence of age-related diseases, including presbycusis and cognitive disorders, have increased with an increase in the geriatric population, the relationship between these two conditions remains unclear.

Objective: To investigate the association between presbycusis and cognitive disorder.

Subjects And Methods: A retrospective review of patient medical records was conducted at a single tertiary university hospital.

A High Neutrophil-to-Lymphocyte Ratio Is Associated with Recovery from Ramsay Hunt Syndrome.

Background: Prediction of the severity and outcomes of Ramsay Hunt syndrome (RHS) is difficult.

Objectives: The aim of this study was to evaluate the predictive power of the neutrophil-to-lymphocyte ratio (NLR) for the severity and outcomes of RHS.

Material And Methods: From 2007 to 2017, a retrospective study of 102 hospitalized patients with RHS was conducted.

Expression of Endoplasmic Reticulum Stress-Related mRNAs in Chronic Otitis Media.

Objectives: Unfolded proteins in the endoplasmic reticulum (ER) cause an ER stress response and can result in various pathologic conditions, including inflammation. Otitis media is the most common disease in otolaryngology and is associated with inflammation. The pathophysiology of chronic otitis media is not well understood; we therefore investigated the expression pattern of ER stress-related mRNAs in chronic otitis media.

Expression of endoplasmic reticulum stress-related mRNA in otitis media with effusion.

Objectives: The endoplasmic reticulum (ER) is an intracellular organelle involved in the synthesis and secretion of proteins. The ER stress response, which protects cells from cytotoxic proteins such as unfolded proteins, is related to several diseases including inflammation. In this study, we investigated the effect of ER stress on the pathophysiology of otitis media with effusion (OME).

Comparative prognosis in patients with Ramsay-Hunt syndrome and Bell's palsy.

Purpose: Patients with Ramsay-Hunt syndrome have a poorer prognosis than patients with Bell's palsy. Factors of metabolic syndrome affecting prognosis were therefore compared between patients with Ramsay-Hunt syndrome and those with Bell's palsy.

Methods: This retrospective study included 106 with Ramsay-Hunt syndrome and 182 with Bell's palsy.

Recurrent Bell's palsy.

Objective: Although recurrent facial palsy was first reported in 1871, the aetiology, definitions, classifications, pathogenesis, treatment options and prognosis have not been clearly determined. There have been no systematic reviews and meta-analyses of recurrent Bell's palsy. The purpose of this study was to evaluate the clinical manifestations of recurrent Bell's palsy through a systematic review and meta-analysis.

Expression of C-type lectin receptor mRNA in otitis media with effusion and chronic otitis media with and without cholesteatoma.

Background & Objectives: C-type lectin receptors (CLRs) are a family of pattern recognition receptors (PRPs). The expression of CLRs has been analyzed in other diseases but has not yet been compared in patients with otitis media with effusion (OME), chronic otitis media (COM) and COM with cholesteatoma (Chole OM). This study therefore evaluated the levels of expression of mRNAs encoding Dectin-1, MR1, MR2, DC-SIGN, Syk, Card-9, Bcl-10, Malt-1, Src, DEC-205, Tim-3, Trem-1, and DAP-12 in patients with OME, COM, and Chole OM.

Association Between High Neutrophil to Lymphocyte Ratio and Delayed Recovery From Bell's Palsy.

Objectives: Factors predictive of the severity of and recovery from Bell's palsy remain unclear. This study evaluated the association between neutrophil to lymphocyte ratio (NLR) and the severity of and recovery from Bell's palsy.

Methods: This retrospective study included 51 patients who were hospitalized with Bell's palsy from 2015 to 2017.

Clinical and Audiologic Characteristics of Tinnitus in Subjects Aged <65 and >65 Years.

Objective: This study compared the characteristics of tinnitus, by audiologic tests and questionnaires, in older and younger subjects.

Materials And Methods: Medical records of 258 outpatients with tinnitus were retrospectively reviewed. Characteristics compared in subjects aged <65 and >65 years included patient history and the results of physical examinations, questionnaires, and audiologic tests.

Association Between Pepsin in the Saliva and the Subjective Symptoms in Patients With Laryngopharyngeal Reflux.

Objectives: Our study was designed to further evaluate the relationships between the saliva pepsin level and the symptoms and quality of life of patients with laryngopharyngeal reflux (LPR).

Study Design: A prospective cohort study without controls.

Setting: Tertiary teaching hospital.

Risk Factors for Complications of Intraoral Removal of Submandibular Sialoliths.

Purpose: Intraoral removal of submandibular sialoliths is a surgical technique for the treatment of sialolithiasis and is reported to have excellent outcomes. The aim of this study was to determine the risk factors leading to complications of this procedure.

Patients And Methods: The medical records of 200 patients who had undergone intraoral removal of sialoliths from January 2006 through June 2015 were retrospectively reviewed.

Invasive Fungal Sinusitis by Lasiodiplodia theobromae in an Patient with Aplastic Anemia: An Extremely Rare Case Report and Literature Review.

Human Lasiodiplodia theobromae infection has not been reported frequently. We report the first case of invasive L. theobromae nasal and neck infection.