Background: Rheumatoid arthritis is a common autoimmune disease with many extra-articular manifestations. Pure red cell aplasia is a rare manifestation of rheumatoid arthritis and is sparsely documented in the literature, with a variable clinical outcome following immunosuppressive therapy.
Case Presentation: A 63-year-old Sinhalese female presented with transfusion-dependent anemia associated with deforming inflammatory arthritis.