First complete and productive cell culture model for members of the genus Iridovirus.

Chilo iridescent virus (CIV; the type strain of the genus Iridovirus) replicates productively in larvae of the boll weevil, Anthonomus grandis. This study focuses on characterizing productive infections of a boll weevil cell line, BRL-AG-3A (AG3A), starting with CIV reared in the waxworm, Galleria mellonella. We show that CIV can be continually and productively passaged to high titer in AG3A cells.

Transmission of Cryptococcus neoformans by Organ Transplantation.

Background: This article describes transmission of Cryptococcus neoformans by solid organ transplantation.

Methods: We reviewed medical records and performed molecular genotyping of isolates to determine potential for donor transmission of Cryptococcus.

Results: Cryptococcosis was diagnosed in 3 recipients of organs from a common donor with an undifferentiated neurologic condition at the time of death.