Bacterial air contamination and the protective effect of coverage for sterile surgical goods: A randomized controlled trial.

Background: There is limited knowledge regarding how long prepared sterile goods can wait before becoming contaminated. We investigated whether surgical goods could be prepared the day before surgery and kept sterile overnight in the operating room, if protected by sterile covers.

Methods: Sterile surgical goods for open-heart surgeries (n=70) were randomized to preparation on the morning of the operation or on the previous evening.

The influence of educational transitions on loneliness and mental health from emerging adults' perspectives.

Educational transitions can influence loneliness and increase mental health issues for young people transitioning between educational stages. The aim was to explore the link between educational transitions and emerging adults' loneliness and mental health and how they perceive they can alleviate and/or improve these issues. Semi-structured qualitative interviews with a total of 12 emerging adults, 10 females and two males aged 18-29 (mean age, 22.

The Joint Media Engagement Scale (JMES): An instrument for measuring shared media use with children aged 1 to 5 years old.

The digital media landscape is rapidly shifting, and some children begin using digital media in infancy. As with book reading, young children need adult guidance to learn from digital media. Joint media engagement (JME) occurs when preschool children and their parents actively use digital media together.

On a healing journey together and apart: A Swedish critical incident technique study on family involvement from a patient perspective in relation to elective open-heart surgery.

Background: As family members affect patient outcomes following open-heart surgery, the objective was to provide updated knowledge on family involvement in to guide future interventions facilitating family involvement.

Aim: The aim was to explore and describe the experiences and actions of important situations of family involvement asexpressed by patients who underwent elective open-heart surgery in Sweden.

Methodological Design And Justification: The critical incident technique (CIT) was used, which is a qualitative research method suitable for clinical problems when a phenomenon is known but the experiences and consequences of it are not.

ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness.

Background: p63 is a transcription factor with intrinsic pioneer factor activity and pleiotropic functions. Transforming growth factor β (TGFβ) signaling via activation and cooperative action of canonical, SMAD, and non-canonical, MAP-kinase (MAPK) pathways, elicits both anti- and pro-tumorigenic properties, including cell stemness and invasiveness. TGFβ activates the ΔNp63 transcriptional program in cancer cells; however, the link between TGFβ and p63 in unmasking the epigenetic landscape during tumor progression allowing chromatin accessibility and gene transcription, is not yet reported.

Toddler's memory and media-Picture book reading and watching video content are associated with memory at 2 years of age.

Memory develops across the course of the first years of life and is influenced by daily experiences, such as exposure to media like books and television. Memory as tapped by Deferred imitation (DI) requires that toddlers form a representation of the target actions that they can later use to reproduce the actions and in addition to measuring memory for real live events, it can also be used to measure memory for events viewed through media. Toddlers are frequently exposed to multiple forms of digital media in addition to more traditional forms of picture book reading.

Experiences of living with funnel chest prior to corrective surgery: An interview study.

Objectives: Pectus excavatum, or funnel chest, causes both physical and psychosocial issues, affecting health-related quality of life. However, the literature on how funnel chest affects daily living prior to corrective surgery is sparse. Therefore, the study aimed to describe the experiences of living with funnel chest prior to correctional surgery.

Effectiveness of reducing bacterial air contamination when covering sterile goods in the operating room setting: a systematic review and meta-analysis.

Background: Postoperative surgical site infection is a serious problem. Coverage of sterile goods may be important to protect the goods from bacterial air contamination while awaiting surgery.

Aim: To evaluate the effectiveness of this practice in a systematic review covering five databases using search terms related to bacterial contamination in the operating room and on surgical instruments.

Translation, cultural adaptation and validation of a patient-reported experience measure for children.

Background: There is no national, validated, generic patient-reported experience measure (PREM) for children under 15 years of age in Sweden. A recent cross-sectional study found no consensus in how children's voices are heard in paediatric health care, as well as a lack of validated questionnaires.

Aim: The aim of this study is to translate, adapt and validate the six versions of the Children's and Young People's PREM for use in a Swedish health care context.

A longitudinal study of the relationship between children's exposure to screen media and vocabulary development.

Aim: This study addresses the scarcity of longitudinal research on the influence of screen media on children. It aims to explore the longitudinal relationship between children's vocabulary development and their exposure to screen media.

Methods: The study, initiated in 2017, included 72 children (37 boys) in Östergötland, Sweden, at three key developmental stages: preverbal (9.

Cervix cytology samples revealed increased methylation of the human markers FAM19A4/miR124-2 up to 8 years before adenocarcinoma.

Introduction: Methylation analysis of the promoter region of tumor-suppressor genes has previously shown high sensitivity for detection of high-grade cervical intraepithelial neoplasia (CIN) and cancer. HPV-testing has a high sensitivity to identify women at risk to develop cancer, and has been implemented in cervical screening programs in several countries. But in most HPV-positive women the infection will clear and they will not develop cancer.

The Family Involvement in Care Questionnaire-An instrument measuring family involvement in inpatient care.

Background: Family involvement in care can be seen as a prerequisite for high-quality family-centered care. It has been identified to improve both patient safety and the quality of care by reducing patient complications and hospital length of stay.

Objective: To develop and evaluate the content validity of a questionnaire measuring family involvement in inpatient care.

The symphony of open-heart surgical care: A mixed-methods study about interprofessional attitudes towards family involvement.

Purpose: The overall aim of this study was to describe the attitudes towards family involvement in care held by nurses and medical doctors working in open-heart surgical care and the factors influencing these attitudes.

Methods: Mixed-methods convergent parallel design. A web-based survey was completed by nurses ( = 267) using the Families' Importance in Nursing Care-Nurses Attitudes (FINC-NA) instrument and two open-ended questions, generating one quantitative and one qualitative dataset.

Interventions for adults with deafblindness - an integrative review.

Purpose: To compile the current research on interventions for rehabilitation aimed at adults (aged 18-65 years) with deafblindness.

Materials And Methods: A comprehensive search was conducted in eight databases. An additional manual search was also carried out.

Cervical neoplasia in relation to socioeconomic and demographic factors - a nationwide cohort study (2002-2018).

Introduction: Cervical cancer is a major cause of mortality and morbidity. We aimed to estimate the association between sociodemographic factors and cervical neoplasia.

Material And Methods: In this Swedish nationwide open cohort study, 4 120 557 women aged ≥15 years at baseline were included between January 1, 2002 and December 31, 2018.

Interventions for children with deafblindness-An integrative review.

Background: Deafblindness is a rare condition, and its prevalence has been reported to be approximately 1 in 27 000 new-borns worldwide. For individuals with deafblindness, lifelong interventions and support are needed to be able to develop communication, be active and preserve a good quality of life. Because little is known about what kind of support and interventions can be offered to children with deafblindness, the aim was to summarize and disseminate research findings regarding this topic.

A method for Boolean analysis of protein interactions at a molecular level.

Determining the levels of protein-protein interactions is essential for the analysis of signaling within the cell, characterization of mutation effects, protein function and activation in health and disease, among others. Herein, we describe MolBoolean - a method to detect interactions between endogenous proteins in various subcellular compartments, utilizing antibody-DNA conjugates for identification and signal amplification. In contrast to proximity ligation assays, MolBoolean simultaneously indicates the relative abundances of protein A and B not interacting with each other, as well as the pool of A and B proteins that are proximal enough to be considered an AB complex.

Qualitative and quantitative aspects of child-directed parental talk and the relation to 2-year-old's developing vocabulary.

Although prior research has independently linked vocabulary development with toddlers' media usage, parental mental state talk (MST), and parent-child conversational turn-taking (CTT), these variables have not been investigated within the same study. In this study, we focus on associations between these variables and 2-year-old's (N = 87) vocabulary. Child vocabulary and digital media use were measured through online questionnaires.

Living an ordinary life - yet not: the everyday life of children and adolescents living with a parent with deafblindness.

Introduction: The family life of people living with one family member with deafblindness has been sparsely described.

Purpose: The aim of the study was to explore how children experience their everyday family life when having a parent with deafblindness.

Methods: An explorative study in which data have been collected by qualitative interviews of children.