Anti-Parkinson's evaluation of leaf extract and underlying mechanism of its phytochemicals.

: Parkinson's disease (PD) is associated with progressive neuronal damage and dysfunction. Oxidative stress helps to regulate neurodegenerative and neuronal dysfunction. Natural compounds could attenuate oxidative stress in a variety of neurological disorders.

The anti-cancer potential of 2,4,6 tris-methyphenylamino1,3,5-triazine compound against mammary glands cancer: Via down-regulating the hormonal, inflammatory mediators, and oxidative stress.

Aim Of The Study: Breast cancer is caused by abnormal growth of the cells and progressed due to the over-expression of estrogen (ER) and progesterone (PR). The current study was designed to evaluate the anti-tumor activity of 2,4,6 tris-methyphenylamino1,3,5-triazine compound (MPAT) in N-nitroso, N-methyl urea (NMU)-induced mammary gland cancer.

Methods: Molecular docking and in-vitro studies were conducted before the in-vivo analysis.

Pharmacological Screening of L for Memory-Enhancing Effect Modulation of Oxidative Stress and Inflammatory Biomarkers.

Alzheimer disease (AD) is a progressive neurodegenerative disorder that is caused by neuroinflammation and oxidative stress. The present study aimed to characterize and then investigate the memory-enhancing potential of methanolic extract in lipopolysaccharide (LPS)-treated mice. characterization was done by using the GCMS technique.

Triazine Derivative as Putative Candidate for the Reduction of Hormone-Positive Breast Tumor: , Pharmacological, and Toxicological Approach.

Breast cancer is a heterogeneous disease that poses the highest incidence of morbidity among women and presents many treatment challenges. In search of novel breast cancer therapies, several triazine derivatives have been developed for their potential chemotherapeutic activity. This study aims to evaluate the N-nitroso-N-methyl urea (NMU)-induced anti-mammary gland tumor activity of 2,4,6 (O-nitrophenyl amino) 1,3,5-triazine (O-NPAT).

In Silico Study and Pharmacological Evaluation of Eplerinone as an Anti-Alzheimer's Drug in STZ-Induced Alzheimer's Disease Model.

Unlabelled: Alzheimer's disease (AD) is the neurodegenerative disorder characterized by impairment of higher intellectual dysfunctions associated with changes in the cognitive, behavioral, and social activities.

Aim Of The Study: The current study was designed to evaluate the potential of aldosterone antagonist in the treatment of AD.

Methodology: The study was conducted on albino mice of either sex ( = 60).

β-Carotene: A Natural Compound Improves Cognitive Impairment and Oxidative Stress in a Mouse Model of Streptozotocin-Induced Alzheimer's Disease.

Alzheimer's disease (AD) is a neurodegenerative disease characterized by a cascade of changes in cognitive, behavioral, and social activities. Several areas of the brain are involved in the regulation of memory. Of most importance are the amygdala and hippocampus.

Markedly Improves Cognitive Functions in Animal Models and Modulate Oxidative Stress Markers in the Brain.

Medicinal plants represent an important source of alternative medicine for the management of various diseases. The present study was undertaken to assess the potential of ethanol (Li.Et) and chloroform (Li.

Experimental and Computational Studies to Characterize and Evaluate the Therapeutic Effect of (L.) Seeds in Alzheimer's Disease.

: Alzheimer's disease (AD) is a neurodegenerative disorder that deteriorates daily life due to loss of memory and cognitive impairment. It is believed that oxidative stress and cholinergic deficit are the leading causes of AD. Disease-modifying therapies for the treatment of AD are a challenging task for this century.

Antioxidants Attenuate Isolation- and L-DOPA-Induced Aggression in Mice.

Aggression is a major hallmark worldwide attributing negative traits in personality. Wide variety of antioxidants is used for the treatment of many ailments. The present study was conducted to evaluate the role of antioxidants such as ascorbic acid (15.