Neuroprotective effect of against monosodium glutamate-induced excitotoxicity.

We aimed to evaluate the neuroprotective effect of against monosodium-glutamate (MSG) induced excitoneurotoxicity in rats. We randomly divided the animals into 11 groups ( = 8) and subjected them to high doses of MSG (2 g/kg body weight) and the test dose (1 week). The test chemicals were extracts of petroleum ether, chloroform, methanol, and water.

Journey of Hydrocotyle sibthorpioides Lam.: From traditional utilization to modern therapeutics-A review.

Hydrocotyle sibthorpioides Lam. (Araliaceae) is a short and edible medicinal herb, which is used in the traditional system of medicines. The review aims to report the current information of H.

Acute oral toxicity evaluation of extracts of in wister albino rats as per OECD 425 TG.

(Family: Apiaceae) is a medicinal plant and is been a part of traditional cuisine. Hence, an acute toxicity study was performed to confirm its safety profile. Female rats (n=5) were randomly divided into 5 groups.

Electroanalysis of some common pesticides using conducting polymer/multiwalled carbon nanotubes modified glassy carbon electrode.

The cyclic voltammetric behaviour of three common pesticides such as isoproturon (ISO), voltage (VOL) and dicofol (DCF) was investigated at glassy carbon electrode (GCE), multiwalled carbon nanotubes modified GCE (MWCNTs/GCE), polyaniline (PANI) and polypyrrole (PPY) deposited MWCNT/GCE. The modified electrode film was characterized by scanning electron microscopy (SEM) and X-ray diffraction analysis (XRD). The electroactive behaviour of the pesticides was realized from the cyclic voltammetric studies.

Topical anti-inflammatory activity of pinda thailam, a herbal gel formulation.

The present study aims to evaluate the topical anti-inflammatory activity of "Pinda thailam", a herbal gel formulation containing aqueous extract of roots of Rubia cordifolia (Rubiaceae) and Hemidesmus indicus (Asclepiadaceae) which are known for their anti-inflammatory activity using the technique of carrageenin induced paw oedema in albino rats. The herbal gel formulation showed significant anti-inflammatory activity comparable to the reference standard Diclofenac sodium gel.

Does oxidative protein damage play a role in the pathogenesis of carbon tetrachloride-induced liver injury in the rat?

Free radicals have been implicated in the pathogenesis of alcohol-induced liver injury in humans and carbon tetrachloride (CCl4)-induced liver injury in rats. The most extensively studied aspect of free radical induced liver injury is lipid peroxidation. Recently it has been found that free radicals can cause oxidative damage to cellular proteins and alter cellular function.