Tailoring the morphological features of sol-gel synthesized mesoporous hydroxyapatite using fatty acids as an organic modifier.

Nowadays, owing to their large surface area, enhanced pore volume, increased porosity, and variable pore size, mesoporous materials, such as mesoporous silica and mesoporous carbon, have attracted significant attention in the areas of physical science and biomedical sciences. Due to their compositional and biological similarities to natural tissues, synthetic nanoscaled mesoporous hydroxyapatite (MPHA) nanoparticles possess good biocompatibility, bioactivity, and osteoconductivity and have recently expanded their applicability in a wide range of fields such as in tissue replacement, drug/gene delivery carriers, and biocompatible coatings. In this study, we defined a novel route to synthesize mesoporous hydroxyapatite nanoparticles by the sol-gel method in the presence of stearic acid (SA), a biocompatible medium chain fatty acid that would function as an organic modifier.

Fabrication and characterization of porous scaffolds for bone replacements using gum tragacanth.

The practice of bone implants is the standard procedure for the treatment of skeletal fissures, or to substitute and re-establish lost bone. A perfect scaffold ought to be made of biomaterials that duplicate the structure and properties of natural bone. However, the production of living tissue constructs that are architecturally, functionally and mechanically comparable to natural bone is the major challenge in the treatment and regeneration of bone tissue in orthopaedics and in dentistry.