Fecal pancreatic elastase-1 and erythrocyte magnesium levels in diabetes type 1 and type 2.

Unlabelled: In both types of diabetes mellitus (DM), type 1 and type 2 (T1DM and T2DM), there are both endocrine and exocrine dysfunctions of the pancreas (PED), as well as disturbances in serum magnesium levels. The aim of this study was to examine the frequency of PED according to the level of fecal elastase-1 (FE-1) in patients with T1DM and T2DM, determining the correlation of the level of FE-1 with certain anthropometric parameters, certain indicators of metabolic regulation of diabetes, and certain nutritive markers of PED.

Materials And Methods: In the examinees, (56 with T1DM (F = 35 and M = 21), 62 with T2DM (F = 30 and M = 32), and 40 in the control group (F = 19 and M = 21)), we examined anthropometric parameters, and using standard biochemical methods, we measured the level of FE-1, magnesium concentration in blood and erythrocytes, and selected blood parameters.

Antioxidative and Protective Actions of Apigenin in a Paracetamol-Induced Hepatotoxicity Rat Model.

Background And Objectives: Apigenin is known to have various pharmacological properties without causing significant toxicity; however, hepatoprotective effect of apigenin is not often reported. The aim of our study was to investigate if the alterations in lipid peroxidation and antioxidant status are in favor to prove the efficacy of apigenin against paracetamol-induced hepatotoxicity.

Methods: The effect of apigenin on paracetamol-induced hepatotoxicity in rats was examined by determining biochemical parameters, histological assessment and oxidative status in liver homogenates.

Glycated hemoglobin A1c as a modern biochemical marker of glucose regulation.

Unlabelled: GLYCATED HEMOGLOBIN STRUCTURE AND SYNTHESIS OF MOLECULE: Glycated hemoglobin A1c, the major fraction of glycated hemoglobin, is formed by irreversible nonenzymatic glycation. Its concentration depends only on the life span of red blood cells and blood glucose levels. CLINICAL SIGNIFICANCE OF GLYCATED HEMOGLOBIN A1c: It is the key parameter for monitoring the regulation of diabetes and for assessing the risk of microvascular complications.

Fibrinolytic parameters, lipid status and lipoprotein(a) in ischemic stroke patients.

Introduction: Ischemic stroke is the third leading cause of mortality and morbidity in most countries in the world. Impaired fibrinolysis, as well as disordered lipid metabolism have been recognized as risk factors for this disease.

Objective: To study some of fibrinolytic parameters, lipid status and lipoprotein(a) - Lp(a) in ischemic stroke patients in Serbia and to examine associations between Lp(a) and fibrinolytic parameters.

[Biochemical markers of atherosclerotic disease].

Introduction: Although the expanding body of research has established firm evidence for the value of some biochemical markers in patients with cardiovascular disease, it has also deluged the clinical and research communities with candidate biomarkers, but very few of them are likely to survive the test of time as useful clinical tool.

Biochemical Markers In Acute Coronary Syndromes: Acute coronary syndrome refers to a constellation of clinical symptoms caused by acute myocardial ischemia. Guidelines for utilization of biochemical markers in acute coronary syndromes are involved in recommendations for use of biomarkers in the initial evaluation of patients with nontraumatic chest symptoms, for diagnosis of myocardial infarction, as well as recommendations for early risk stratification of subsequent death and/or recurrent ischemic event.

Influence of sodium monoketocholate on the hypolipidemic activity of lovastatin in healthy and diabetic rats.

Recent findings regarding the physiological transport mechanisms and metabolism of bile acids have led to an increased interest in their synthetic derivatives, especially as transmucous transporters. The aim of this study was to examine the influence of the synthetic sodium salt of monoketocholic acid (Na-MKHA) on the hypolipidemic activity of lovastatin. The effects of a 7 days administration of lovastatin (20 mg/kg b.