Enhanced Osteogenesis by Molybdenum Disulfide Nanosheet Reinforced Hydroxyapatite Nanocomposite Scaffolds.

The advances in the arena of biomedical engineering enable us to fabricate novel biomaterials that provide a suitable platform for rapid bone regeneration. Herein, we have investigated the in vitro and in vivo osteogenic differentiation, proliferation, and bone regeneration capability of molybdenum disulfide nanosheets (MoSNSs) reinforced HAP nanocomposite scaffolds. The MG-63 cells were incubated with HAP and HAP/MoSNSs nanocomposite and followed for various cellular activities.

Nitrogen doped carbon quantum dots demonstrate no toxicity under conditions in a cervical cell line and in Swiss albino mice.

Carbon quantum dots (CQDs) and their derivatives have potential applications in the field of biomedical imaging. Toxicity is one of the critical parameters that can hamper their success in biological applications. In this context, our goal was to systematically investigate both and toxicity of nitrogen doped carbon quantum dots (NCQDs).

Graphene Oxide Synergistically Enhances Antibiotic Efficacy in Vancomycin-Resistant .

The current study highlights a new polyvalent inhibitor approach based on Vancomycin conjugated with graphene oxide (Van@GO) against a Vancomycin-resistant (VRSA) strain. Physicochemical characteristics of the prepared Van@GO composites were studied using UV-vis and FTIR spectroscopy techniques. Characterization results confirm the attachment of Vancomycin to the graphene oxide.

Excellent storage stability and sensitive detection of neurotoxin quinolinic acid.

Quinolinic acid (QA) is a metabolite of tryptophan degradation obtained through kynurenine pathway, produced naturally in the mammalian brain as well as in the human cerebrospinal fluid. The presence of QA ~10-40µM is a clear indicator of many neurological disorders as well as deficiency of vitamin B in human being. In the present work; rapid, sensitive and cost-effective bio-electrodes were prepared to detect the trace amount of endogenous neurotoxin (QA).