Analysis of differential expression of hair follicle tissue transcriptome in Hetian sheep undergoing different periodic changes.

Background: This study provides new information on long non-coding RNA (lncRNA) and messenger RNA (mRNA) expression profiles in the hair follicles of Hetian sheep the sequencing and analysis of the transcriptome of skin hair follicles during three periods of periodicity change. This is important for improving the quality of carpet wool, providing a preliminary basis for further research on the targeting relationship of these mRNAs and their target genes, and providing a scientific basis for marker-assisted selection of Hetian sheep.

Methods: The periodic variation of anagen (P I, May,  = 3), catagen (p II, October,  = 3), and telogen (p III, January,  = 3) of the skin hair follicle tissue of three Hetian sheep ewes were selected.