Recently, the number of users and the demand for live-streaming services have increased. This has exponentially increased the traffic to such services, and live-streaming service platforms in Korea use a grid computing system that distributes traffic to users and reduces traffic loads. However, ensuring security with a grid computing system is difficult because the system exchanges general user traffic in a peer-to-peer (P2P) manner instead of receiving data from an authenticated server.
View Article and Find Full Text PDFCell growth is positively controlled by the phosphoinositide 3-kinase (PI3K)-target of rapamycin (TOR) signaling pathway under conditions of abundant growth factors and nutrients. To discover additional mechanisms that regulate cell growth, here we performed RNAi-based mosaic analyses in the fat body, the primary metabolic organ in the fly. Unexpectedly, the knockdown of the () gene markedly decreased cell size and body size.
View Article and Find Full Text PDFThe function of AarF domain-containing kinase 1 (ADCK1) has not been thoroughly revealed. Here we identified that ADCK1 utilizes YME1-like 1 ATPase (YME1L1) to control optic atrophy 1 (OPA1) and inner membrane mitochondrial protein (IMMT) in regulating mitochondrial dynamics and cristae structure. We firstly observed that a serious developmental impairment occurred in Drosophila ADCK1 (dADCK1) deletion mutant, resulting in premature death before adulthood.
View Article and Find Full Text PDFBiochem Biophys Res Commun
January 2019
Wnt signaling pathway plays critical roles in body axes patterning, cell fate specification, cell proliferation, cell migration, stem cell maintenance, cancer development and etc. Deregulation of this pathway can be causative of cancer, metabolic disease and neurodegenerative disease such as Parkinson`s disease. Among the core components of Wnt signaling pathway, we discovered that Dishevelled (Dsh) interacts with ULK1 and is phosphorylated by ULK1.
View Article and Find Full Text PDFPurpose: The purpose of this study was to elucidate the differences of the prevalence and diameter of the posterior superior alveolar artery (PSAA) and the distance of its inferior border from the alveolar crest on computed tomography (CT) images according to age and sex.
Materials And Methods: CT images of maxilla in 200 patients were randomly selected from patients who underwent CT imaging at Yonsei University Dental Hospital, and analyzed. The prevalence of the PSAA in maxillary sinus and the distance of its inferior border from the alveolar crest in the premolar and molar area were measured.