Web-based cognitive interventions on subjective cognitive impairment in cancer survivors: A systemic review.

Objective: Cancer survivors have experienced subjective cognitive impairment (SCI) when they received cancer diagnoses or treatments. Their psychosocial and emotional statuses were also impacted. With the advancement of web technologies, web-based cognitive interventions have been implemented in the management and the alleviation of the SCI, the psychosocial distress, and the emotional distress in cancer survivors.

NKAPL facilitates transcription pause-release and bridges elongation to initiation during meiosis exit.

Transcription elongation, especially RNA polymerase II (Pol II) pause-release, is less studied than transcription initiation in regulating gene expression during meiosis. It is also unclear how transcription elongation interplays with transcription initiation. Here, we show that depletion of NKAPL, a testis-specific protein distantly related to RNA splicing factors, causes male infertility in mice by blocking the meiotic exit and downregulating haploid genes.

Corona electric field triggered N lasing from a femtosecond laser filament in air.

The emission of N lasing at 391 nm from 800 nm femtosecond laser filament in air at 1 atm presents significant challenges due to the quenching effect induced by oxygen molecules. We introduce a simple technique for the 391 nm N lasing emission induced by a corona electric field-assisted femtosecond filament in air. This technique greatly addresses the challenge of exciting a 391 nm lasing from 800 nm femtosecond laser filament in air at 1 atm.

Enzyme-independent functions of HDAC3 in the adult heart.

The cardioprotective effects of histone deacetylase (HDAC) inhibitors (HDIs) are at odds with the deleterious effects of HDAC depletion. Here, we use HDAC3 as a prototype HDAC to address this contradiction. We show that adult-onset cardiac-specific depletion of HDAC3 in mice causes cardiac hypertrophy and contractile dysfunction on a high-fat diet (HFD), excluding developmental disruption as a major reason for the contradiction.

Preoperative comprehensive risk estimation for axillary lymph node metastasis in breast cancer: development and verification of a network-based prediction model.

To prevent the overaggressive treatment of axillary lymph nodes (ALNs) in breast cancer, it is necessary to develop a convenient analysis method that accurately and comprehensively reflects whether ALNs are metastatic or nonmetastatic. We retrospectively analyzed data from patients who underwent surgery for breast cancer at the Weifang Hospital of Traditional Chinese Medicine between January 2019 and June 2023. Binary logistic regression analysis was used to predict the metastasis status of ALNs.

Deep proximal gradient network for absorption coefficient recovery in photoacoustic tomography.

The optical absorption properties of biological tissues in photoacoustic (PA) tomography are typically quantified by inverting acoustic measurements. Conventional approaches to solving the inverse problem of forward optical models often involve iterative optimization. However, these methods are hindered by several challenges, including high computational demands, the need for regularization, and sensitivity to both the accuracy of the forward model and the completeness of the measurement data.

Bioinspired balloon catheter integrated with stretchable "flounder" electrodes under high voltage for uniform pulsed field ablation.

Atrial fibrillation leads to severe diseases such as heart failure and strokes. While catheter ablation is prevalent for the treatment, existing techniques hardly can achieve both tissue selectivity and ablation uniformity. Here, we propose a bioinspired strategy for balloon-based pulsed field ablation (PFA) systems based on "flounder" electrodes.

Probe-type optical fiber sensors for electric field distribution measurement.

This paper reports a compact fiber optical electric field (E-field) sensor aiming for the precise detection of transient E-field distributions. Here, a reflective polarization-reciprocal optical path is proposed, which inherently mitigates the temperature-induced birefringence interference of the electro-optical crystal without the need for additional optical elements, thereby facilitating a reduced-size sensing probe. Furthermore, an adaptive particle swarm optimization (A-PSO) algorithm has been utilized for the first time to optimize the insulation structure of the optical E-field sensor, which significantly suppresses field distortion within the sensing region by 50%.

Viromics-based precision diagnosis of reproductive abnormalities in cows reveals a reassortant Akabane disease virus.

Background: At the end of 2021, an epidemic of reproductive abnormalities in cows occurred in Jilin Province, China, posing an urgent need for a rapid diagnosis.

Results: To identify the cause of the disease, a total of 172 samples were collected from 21 dead calves and 45 aborting or pregnant cows in 10 farms across the province. Routine PCR or RT-PCR detection did not find any common abortion-related agents.

Ultrasensitive electrochemiluminescencent multivalent aptamer sensor based on energy and electron transfer dual quenching tactics.

An efficient "on-off-on" electrochemiluminescence (ECL) aptasensor utilizing dual-mechanism quenching was constructed for detecting furanyl fentanyl (FuF). The first signal "on" state was achieved by novel dual-ligand zinc metal-organic frameworks (Zn-MOFs), which were synthesized by self-assembly reaction using zinc atom clusters as metal nodes, achieving strong and stable ECL emission. The "off" state was realized by the energy and electron quenching effect of copper-doped WO.

JQR-Net: joint quantitative reconstruction network for dual-modal photoacoustic and optical coherence tomography imaging.

Photoacoustic (PA) and optical coherence tomography (OCT) imaging are complementary imaging modalities with distinct contrast mechanisms, penetration depths, and spatial resolutions. Integrating these two modalities into a dual-modal PA-OCT imaging system enables the simultaneous acquisition of multimodal signals within a single scan. This integration supports quantitative reconstruction of tissue characteristics, offering a more precise and comprehensive analysis than single-modal imaging.

Effects of overexpression via the NRF2 / HO1 / NQO1 pathway on oral cancer cells proliferation, migration, and apoptosis.

Objective: Herein, we explored the influences of overexpression on oral cancer cells proliferation, migration, and apoptosis via evaluation of its interactions with nuclear factor erythroid 2-like 2 (NRF2).

Design: CAL-27 and DOK cells were transfected with a overexpressing lentivirus. Next, we utilized Western blot and quantitative real-time polymerase chain reaction (qRT-PCR) analyses to evaluate BRCA1, NRF2, and their target gene expressions.

A feasibility study of a couple-based illness perception intervention for couples coping with colorectal cancer.

Purpose: As a special psychological variable, illness perception significantly affects the cancer adaptions of colorectal cancer couples. No studies focus on facilitating cancer adaption by targeting the illness perception in colorectal cancer couples. This research attempted to explore the feasibility, acceptability, and potential effectiveness of an illness perception intervention program designed for couples with colorectal cancer, guided by a self-regulation common sense model.

Dual-Mechanism Quenching Electrochemiluminescence System by Coupling Energy Transfer with Electron Transfer for Sensitive Competitive Aptamer-Based Detection of Furanyl Fentanyl in Food.

Resonance energy transfer (RET) quenching is significantly important for developing electrochemiluminescence (ECL) sensors, but RET platforms face challenges like interference from other fluorescent substances and reliance on energy transfer efficiency. This study used Zn-PTC, formed by zinc ions coordinated with perylene-3,4,9,10-tetracarboxylate, as a dual-mechanism quencher to reduce the ECL intensity of carbon nitride nanosheets (Tg-CNNSs). CoO/NiCoO acts as a coreaction promoter, enhancing and stabilizing the luminescence of Tg-CNNSs.

Cryopreservation of Medicinal Plant Seeds: Strategies for Genetic Diversity Conservation and Sustainability.

The depletion of medicinal plant resources leads to the irreversible loss of their genetic diversity. The preservation of medicinal plant germplasm using cryobanks is crucial for maintaining the sustainability of these resources. This study examined the efficacy of cryopreservation on 164 medicinal plant seeds, identified general principles for preserving medicinal plant seeds at ultra-low temperatures, and established a cryobank for dry-sensitive medicinal plant seeds.

Horizontal analysis and longitudinal cohort study of chronic renal failure correlates and cerebral small vessel disease relationship using peak width of skeletonized mean diffusivity.

Background And Purpose: Peak width of skeletonized mean diffusivity (PSMD) is an MRI-based biomarker that may reflect white matter lesions (WML). PSMD is based on skeletonization of MR DTI data and histogram analysis. Both chronic renal failure (CRF) and WML may be affected by multisystemic small-vessel disorder.

Rational Design of Live Biotherapeutic Products for the Prevention of Clostridioides difficile Infection.

Clostridioides difficile infection (CDI) is a major cause of healthcare- and antibiotic-associated diarrhea. While fecal microbiota transplantation (FMT) shows promise for recurrent CDI, its mechanisms and long-term safety are not fully understood. Live biotherapeutic products (LBPs) using pre-defined bacterial consortia offer an alternative option, but the rational designing LBPs remains challenging.

Fundamental Understanding of Interface Chemistry and Electrical Contact Properties of Bi and MoS.

The interface properties and thermal stability of bismuth (Bi) contacts on molybdenum disulfide (MoS) shed light on their behavior under various deposition conditions and temperatures. The examination involves extensive techniques including X-ray photoelectron spectroscopy, scanning tunneling microscopy (STM), and scanning tunneling spectroscopy (STS). Bi contacts formed a van der Waals interface on MoS regardless of deposition conditions, such as ultrahigh vacuum (UHV, 3 × 10 mbar) and high vacuum (HV, 4 × 10 mbar), while the oxidation on MoS has been observed.