Advancements in research on the association between the biological CLOCK and type 2 diabetes.

Due to the Earth's rotation, the natural environment exhibits a light-dark diurnal cycle close to 24 hours. To adapt to this energy intake pattern, organisms have developed a 24-hour rhythmic diurnal cycle over long periods, known as the circadian rhythm, or biological clock. With the gradual advancement of research on the biological clock, it has become increasingly evident that disruptions in the circadian rhythm are closely associated with the occurrence of type 2 diabetes (T2D).

Visual Dissemination of Intangible Cultural Heritage Information Based on 3D Scanning and Virtual Reality Technology.

In order to meet the needs of modern people for the acquisition of intangible cultural heritage information, the authors propose a research method that combines 3D scanning and virtual reality technology. Taking the production process of Xiuyu as an example, using Unity3D virtual reality technology combined with a digital platform, 3D modeling of Xiuyu is carried out, so that people can view the intangible cultural heritage information intuitively. The experimental results show that after using this method, more than 60% of more than 1000 people surveyed in the questionnaire want to experience intangible cultural heritage.

[An experimental study on rabbit liver by 3.0 Tesla magnetic resonance diffusion-weighted imaging].

Objective: To explore the methodology as well as the features, quantificational index, and reference standard of 3.0 Tesla magnetic resonance (MR) diffusion-weighted imaging (DWI) on the normal rabbit's liver.

Methods: Twenty New Zealand white rabbits were enrolled and DWI was performed after anesthetics with multi-b values at 3.

[Modification of the method for preparing rabbit liver VX2 tumor model and its MRI findings].

Objective: To improve the method for preparing rabbit VX2 liver tumor model and observe the magnetic resonance imaging (MRI) features of the implanted tumors.

Methods: Sixteen adult New Zealand white rabbits were assigned randomly into 4 equal groups, and VX2 tumor tissues were implanted into the right and left liver lobes with spiral CT guidance. Plain and contrast-enhanced MR scan and pathological analysis were performed in different stages (14, 18, 22 and 26 days) after tumor implantation.

[Quantitative study of dynamic magnetic resonance perfusion-weighted imaging in rabbit models of implanted hepatic VX2 tumor].

Objective: To investigate the possibility of dynamic magnetic resonance (MR) perfusion-weighted imaging (PWI) in rabbit models of implanted hepatic VX2 tumor.

Methods: MRI and PWI images were obtained from 16 rabbit models of implanted hepatic VX2 tumor and 4 normal rabbits at 14, 18, 22, and 26 days after tumor implantation, respectively, and the mean time to enhancement (MTE) and maximum slope of increase (MSI) were estimated and compared with pathological changes.

Results: In the rabbit models of implanted hepatic tumor the MTE tended to increase and MSI to descend 14, 18, 22, and 26 days after tumor implantation, showing significant differences from the control group.

[Preliminary quantitative study of dynamic magnetic resonance diffusion tensor imaging in rabbit models implanted with hepatic tumor grafts from VX2].

Objective: To investigate the feasibility of dynamic magnetic resonance diffusion tensor imaging (DTI) in rabbit models with implanted VX2 hepatic tumor grafts.

Methods: MRI and DTI images were obtained from 16 rabbit models with implanted VX2 hepatic tumor grafts (14, 18, 22, and 26 days after tumor implantation, respectively) and 4 normal rabbits. The average diffusion coefficient (ADC) and exponential ADC (eADC) were estimated and compared against pathological findings.

Quantitative evaluation of diffusion-weighted magnetic resonance imaging of focal hepatic lesions.

Aim: To explore the quantitative analysis of diffusion-weighted magnetic resonance imaging (DWMRI) in differential diagnosis of focal hepatic lesions.

Methods: DWMRI was performed in 149 hepatic lesions, including hepatocellular carcinoma (34 cases), hepatic metastases (37 cases), cavernous hemangioma (42 cases), hepatic cyst (36 cases). Apparent diffusion coefficient (ADC) values were evaluated using four different b values in different sequences.

Evaluation of diffusion weighted imaging of magnetic resonance imaging in small focal hepatic lesions: a quantitative study in 56 cases.

Background: Diffusion-weighted imaging (DWI) as a new technique of magnetic resonance imaging (MRI) is used to detect focal hepatic lesions. This study was designed to evaluate the significance of DWI to differentiate focal hepatic lesions less than 3 cm in diameter by the quantitation of apparent diffusion coefficient (ADC) values.

Methods: DWI using 1.

[Quantitative study of diffusion weighted imaging on magnetic resonance imaging in focal hepatic lesions less than 3 cm].

Objective: To evaluate the characteristics of MR imaging of hepatic lesions using measurement of apparent diffusion coefficient (ADC) value of hepatic lesions on diffusion weighted imaging.

Methods: MR diffusion weighted images were obtained in patients with 97 hepatic lesions (22 hepatocellular carcinomas, 21 metastatic tumors, 28 hemangiomas, 26 cysts). ADC values were evaluated with different sequences.