Robust formation control of multiple aerial robotic vehicles using near neighbor cyclic deviation with time-varying disturbances.

Cooperative formation flight of multiple aerial robotic vehicles (ARVs) is extensively adopted in emergency rescue and collaborative transport. But the time-varying complex disturbances are inevitable in the cooperative formation flight of multiple ARVs, which can affect the formation stability of multi-ARV systems. This paper investigates the robust formation control problems for multiple ARVs with time-varying disturbances.

Fully biobased and robust antibacterial cellulose aerogel for uranium extraction.

Developing efficient adsorbent is imperative for the utilization of uranium resources in seawater. Marine microorganisms and bacteria play an important role in the process of adsorption of uranium. In this work, a completely bio-based antimicrobial aerogel (quaternary cellulose/chitosan aerogel-QCNF/CS) was prepared by cross-linking quaternary cellulose nanofibers (QCNF) and chitosan (CS) via citric acid (CA).

A novel sensitizer reduces EGFR-TKI resistance by regulating the PI3K/Akt/mTOR pathway and autophagy.

Background: The incidence and mortality of lung cancer are high, and treatment with epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is the preferred first-line treatment for patients suffering from non-small cell lung cancer (NSCLC) with EGFR mutations. However, EGFR-TKI resistance leads to treatment failure. Yifei-Sanjie pill (YFSJ) is a novel type of Chinese patent medicine for lung cancer.

Enhancing Water Electrolysis through Interfacial Design of Nickel Foam.

Water electrolysis recognizes nickel foam (NF) as an effective current collector due to its excellent conductivity. However, recent studies highlighted NF's effect on the efficacy of various electrocatalytic reactions, primarily due to the presence of electroactive chemical species at its interface. In contrast, numerous reports suggested that NF has a negligible impact on overall electrocatalytic activity.

Novel plasma cytokines identified and validated in children during lead exposure according to the new updated BLRV.

Lead is a pervasive environmental contaminant with significant health risks, particularly to children. It is known for its neurotoxic and immunotoxic effects, causing developmental, cognitive, and behavioral impairments. Despite extensive research, the mechanisms of lead toxicity remain unclear.

[Distribution, Accumulation Characteristics, and Risk Assessment of Heavy Metals in Vegetable Soils of Different Planting Years].

To ascertain the influence of prolonged planting on the distribution and accumulation of heavy metals in protected vegetable soil, samples from typical vegetable planting areas in Shenyang were gathered to evaluate the distribution features of Cr, Ni, Cu, Zn, Cd, and Pb in such soil. The Hakanson index, heavy metal risk assessment standard, and secondary phase to primary ratio methods were employed to evaluate the ecological hazard of soil in the research area, while the human health risk model was utilized to evaluate the health of inhabitants. The findings indicated that：① The amount of heavy metals Zn, Cr, Cu, Ni, Pb, and Cd in the topsoil （0~20 cm） of protected vegetable land in the study region decreased successively, and the content of heavy metals in the topsoil increased with the extension of planting years, of which Cd, Zn, and Cu increased most obviously, with maximum increases of 219%, 189%, and 134%, respectively.

Association between family income to poverty ratio and severe headache/migraine in the American adults: data from NHANES 1999-2004.

Background: The relationship between family income to poverty ratio (PIR) and severe headache/migraine remains unclear.

Methods: Data for this cross-sectional study were obtained from NHANES 1999-2004. PIR was the exposure variable, and severe headache/migraine was the dependent variable.

Multi-environment QTL mapping identifies major genetic loci influencing soybean main stem node architecture.

Soybean plant architecture has a significant impact on yield potential, but the genetic underpinnings of key architectural traits remain elusive. The primary objective of this study was to explore the genetic foundations underlying main stem node number (MSN) in soybeans. Recombinant inbred lines (RILs) contained a 234 individual derived from crosses between two cultivars Zhonghuang35 (ZH35) and Jindou21 (JD21) was evaluated for seed hardness across 3 years (2013, 2014, and 2015 in Gansu).

Akkermansia muciniphila Promotes SIgA Production and Alters the Reactivity Toward Commensal Bacteria in Early-Weaned Piglets.

Background: Secretory IgA (SIgA) is the first line of defense in protecting the intestinal epithelium against pathogenic bacteria, regulating gut microbiota composition, and maintaining intestinal homeostasis. Early weaning strategies may disrupt SIgA levels in piglet intestines, causing a decline in immune response and early weaning stress. However, the specific microbial mechanisms modulating SIgA in early-weaned piglets are not well understood.

Yi-Fei-San-Jie Chinese medicine formula reverses immune escape by regulating deoxycholic acid metabolism to inhibit TGR5/STAT3/PD-L1 axis in lung cancer.

Background: Yi-Fei-San-Jie Formula (YFSJF), a proprietary medicine of the First Affiliated Hospital of Guangzhou University of Chinese Medicine, has been widely used in clinical practice for several years and is currently being tested in randomized controlled trials for early-stage lung cancer in China. However, the mechanisms by which YFSJF affects lung cancer biology, particularly the immune microenvironment and metabolic processes, remain poorly understood.

Purpose: This study aims to explore how YFSJF modulates the immune microenvironment and metabolism in lung cancer, specifically its unique role in inhibiting immune evasion by targeting the TGR5/STAT3/PD-L1 pathway, which has not previously been reported.

Computed tomography-based radiomic model for the prediction of neoadjuvant immunochemotherapy response in patients with advanced gastric cancer.

Background: Neoadjuvant immunochemotherapy (nICT) has emerged as a popular treatment approach for advanced gastric cancer (AGC) in clinical practice worldwide. However, the response of AGC patients to nICT displays significant heterogeneity, and no existing radiomic model utilizes baseline computed tomography to predict treatment outcomes.

Aim: To establish a radiomic model to predict the response of AGC patients to nICT.

SNAP25-induced MYC upregulation promotes high-grade neuroendocrine lung carcinoma progression.

Background: This study investigated the expression and role of Synaptosome associated protein 25 (SNAP25) in high-grade neuroendocrine carcinoma (HGNEC).

Methods: We used differentially expressed analysis and weighted gene co-expression network analysis (WGCNA) to identify key genes and modules in HGNEC. KEGG and GO analyses helped understand these genes' roles, and ROC curves assessed their diagnostic value.

Primary spinal epidural abscess: magnetic resonance imaging characteristics and diagnosis.

Rationale And Objective: To investigate the MR characteristics of phlegmonous stage and abscess stage primary spinal epidural abscess.

Materials And Methods: This study retrospectively analyzed the clinical and imaging characteristics of 27 cases of pathologically confirmed primary spinal epidural abscess. Predisposing conditions of all patients were collected.

A strategy involving the use of 3D self-supporting B·N co-doped carbon nanofiber composite solid polymer electrolytes to stabilize the interface between polymer electrolytes and lithium metal.

All-solid-state batteries (ASSBs) have gained significant attention in the field of energy storage owing to their enhanced safety features based on the nonflammable solid-state electrolyte (SSE). To achieve high energy density, lithium metal is commonly considered the best choice as an anode material. However, the compatibility issues at the interface between polymer electrolytes and lithium metal pose significant challenges to their practical implementation.

EMS-induced missense mutation in TaCHLI-7D affects leaf color and yield-related traits in wheat.

Mutations in TaCHLI impact chlorophyll levels and yield-related traits in wheat. Natural variations in TaCHLI-7A/B influence plant productivity, offering potential for molecular breeding. Chlorophyll is essential for plant growth and productivity.

Prediction and verification of benignancy and malignancy of pulmonary nodules based on inflammatory related biological markers.

Objective: Inflammation plays an important role in the transformation of pulmonary nodules (PNs) from benign to malignant. Prediction of benignancy and malignancy of PNs is still lacking efficacy methods. Although Mayo or Brock model have been widely applied in clinical practices, their application conditions are limited.

Perioperative dexmedetomidine-induced delirium in a patient with schizophrenia: a case report.

Background: Dexmedetomidine is a selective α2 receptor agonist with sedative, analgesic, anxiolytic, and anti-sympathetic effects. Dexmedetomidine is widely used for various surgical procedures performed under general anaesthesia and sedation in the intensive care unit. Dexmedetomidine was known to relieve or improve the symptoms of delirium.

Stearoyl-CoA desaturase 1 is targeted by EBV-encoded miR-BART20-5p and regulates cell autophagy, proliferation, and migration in EBV-associated gastric cancer.

Epstein-Barr virus (EBV) is the first human oncogenic virus known to express microRNAs (miRNAs), which are closely associated with the development of various tumors, including nasopharyngeal and gastric cancers. Stearoyl-CoA Desaturase 1 (SCD1) is a key enzyme in fatty acid synthesis, highly expressed in numerous tumors, promoting tumor growth and metastasis, making it a potential therapeutic target. In this study, we found that SCD1 expression in EBV-associated gastric cancer (EBVaGC) was significantly lower than in EBV-negative gastric cancer (EBVnGC) at both cellular and tissue levels.

Biosensor with Microchannel for Broadband Dielectric Characterization of Nanoliter Cell Suspensions up to 110 GHz.

Cell dielectric property measurement holds significant potential for application in cell detection and diagnosis due to its label-free and noninvasive nature. In this study, we developed a biosensor designed to measure the permittivity of liquid samples, particularly cell suspensions at the nanoliter scale, utilizing microwave and millimeter wave coplanar waveguides in conjunction with a microchannel. This biosensor facilitates the measurement of scattering parameters within a frequency domain ranging from 1 GHz to 110 GHz.

Treatment preferences and current practices regarding open tibial shaft fractures.

Purpose: The purpose of this study was to reveal the treatment preferences and current practices regarding open tibial shaft fracture (OTSF).

Patients And Methods: Online surveys of treatment preferences and current practice of OTSF were conducted by orthopedic trauma doctors from various medical institutions in Zhejiang Province. The survey contains three modules.

Varieties of P fractions in biochar-amended reconstructed soils as impacted by freeze-thaw interference.

With low cost and stable chemical properties, biochar has great potential in environmental pollution control and improving soil quality. Reusing tailings slag to reconstruct soil ecosystems and applying amendments such as biochar to enhance soil quality are significant for restoring waste mine lands. Phosphorus (P) as the restrictive nutrition element for plant growth is easily affected by freeze-thaw cycles (FTCs).