Solvent-modulated preparation of lead-free CsBiIpolycrystalline film for high-performance photodetectors.

Lead-free cesium bismuth iodide (CsBiI) perovskite exhibits extraordinary optoelectronic properties and attractive potential in various optoelectronic devices, especially the application for photodetectors. However, most CsBiIphotodetectors demonstrated poor detection performance due to the difficulty in obtaining high-quality polycrystalline films. Therefore, it makes sense to modulate the preparation of high-quality CsBiIpolycrystalline films and expand its applications.

Cytoplasmic G6PDs modulate callus formation in Arabidopsis root explants through regulation of very-long-chain fatty acids accumulation.

Glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme in the pentose phosphate pathway, impacts cancer cell proliferation and plant stress responses. However, its role in plant cell dedifferentiation and callus formation is not well understood. This study explores the function of cytoplasmic G6PD isoforms in Arabidopsis pericycle cell reprogramming into callus by employing a suite of mutant analyses, qRT-PCR, and GC-MS.

Multifunctional Artificial Electric Synapse of MoSe-Based Memristor toward Neuromorphic Application.

Research on memristive devices to seamlessly integrate and replicate the dynamic behaviors of biological synapses will illuminate the mechanisms underlying parallel processing and information storage in the human brain, thereby affording novel insights for the advancement of artificial intelligence. Here, an artificial electric synapse is demonstrated on a one-step Mo-selenized MoSe memristor, having not only long-term stable resistive switching characteristics (reset 0.51 ± 0.

Descriptor for electro-oxidation of glycerol with high-efficiency bifunctional Cu-N single atom catalyst and coupled with hydrogen evolution/carbon dioxide reduction.

Electrochemical glycerol oxidation reaction (GOR) presents a promising approach for converting excess glycerol (GLY) into high-value-added products. However, the complex mechanism and the challenge of achieving selectivity for diverse products make GOR difficult to address in both experimental and theoretical studies. In this work, three nitrogen-doped graphene-supported copper single-atom catalysts (CuN@Gra SACs, x = 2-4) were selected as the model system due to their simple structure, excellent conductivity and high structural stability.

Theoretical modeling and modal analysis of multi-element coupled transducers.

Low-frequency transducers are considerably smaller than the wavelength. When multiple low-frequency transducers are closely packed, they couple with the surrounding water and form a transducer-water-transducer coupling structure called multi-element coupled transducers (MCT). This study presents a theoretical model of the MCT based on radiation and mutual radiation theory and analyzes it under multiple resonance frequencies and vibration modes.

Screening of single-atomic catalysts loaded on two-dimensional transition metal dichalcogenides for electrocatalytic oxygen reduction via high throughput ab initio calculations.

The design and screening of low cost and high efficiency oxygen reduction reaction (ORR) electrocatalysts is vital in the realms of fuel cells and metal-air batteries. Existing studies largely rely on the calculation of absorption free energy, a method established 20 years ago by Jens K. Nørskov.

Self-Sustained Biophotocatalytic Nano-Organelle Reactors with Programmable DNA Switches for Combating Tumor Metastasis.

Metastasis, the leading cause of mortality in cancer patients, presents challenges for conventional photodynamic therapy (PDT) due to its reliance on localized light and oxygen application to tumors. To overcome these limitations, a self-sustained organelle-mimicking nanoreactor is developed here with programmable DNA switches that enables bio-chem-photocatalytic cascade-driven starvation-photodynamic synergistic therapy against tumor metastasis. Emulating the compartmentalization and positional assembly strategies found in living cells, this nano-organelle reactor allows quantitative co-compartmentalization of multiple functional modules for the designed self-illuminating chemiexcited PDT system.

Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathy.

Long-term potentiation (LTP) and long-term depression (LTD) are widely used to study synaptic plasticity. However, whether proteins regulating LTP and LTD are altered in cognitive disorders and contribute to disease onset remains to be determined. Herein, we induced LTP and LTD in the hippocampal CA3-CA1 Schaffer collateral pathway, respectively, and then performed proteomic analysis of the CA1 region.

Effect of comorbid allergic diseases on attention-deficit hyperactivity disorder symptoms and sleep: A cross-sectional study.

Introduction: Recent studies have shown a close relationship between attention-deficit hyperactivity disorder (ADHD) and allergic diseases in children. Regrettably, few studies have investigated the effect of comorbid allergies on ADHD symptoms and sleep, in particular, it is unclear whether comorbid allergic conditions further exacerbate sleep problems in children with ADHD.

Objective: To investigate the effect of comorbid allergic on symptoms and sleep in children with ADHD.

Assessing genomic diversity and signatures of selection in Qingyuan Wapiti.

Red deer is a species of family Cervidae that is widely distributed in the world and is often raised to provide antlers, as a trophy or traditional medicine materials, and meat. Currently, the whole genomic data for red deer are very limited. Qingyuan Wapiti (QYW), China's first breed of red deer by artificial breeding, is well known for its high yield of antlers and large body size.

Heavy metal(loid)s accumulation and human health risk assessment in wheat after long-term application of various urban and rural organic fertilizers.

Composting urban and rural wastes into organic fertilizers for land application is considered the best way to dispose of and recycle waste resources. However, there are some concerns about the long-term effects of applying various organic fertilizers on soils, food safety, and health risks derived from heavy metal(loid)s (HMs). A long-term field experiment was conducted to evaluate the effects of continuous application of chicken manure compost (CM), sewage sludge compost (SSC), and domestic waste compost (DWC) for wheat on the accumulation, transfer, and health risks of HMs.

Targeting Synthesis of Diatomic Catalysts by Selective Etching and Sequential Adsorption of Metal Atom.

Diatomic catalysts featuring a tunable structure and synergetic effects hold great promise for various reactions. However, their precise construction with specific configurations and diverse metal combinations is still challenging. Here, a selective etching and metal ion adsorption strategy is proposed to accurately assign a second metal atom (M) geminal to the single atom site (M-N) for constructing diatomic sites (e.

Pervasive RNA-binding protein enrichment on TAD boundaries regulates TAD organization.

Mammalian genome is hierarchically organized by CTCF and cohesin through loop extrusion mechanism to facilitate the organization of topologically associating domains (TADs). Mounting evidence suggests additional factors/mechanisms exist to orchestrate TAD formation and maintenance. In this study, we investigate the potential role of RNA-binding proteins (RBPs) in TAD organization.

Enhancing Neuron Activity Promotes Functional Recovery by Inhibiting Microglia-Mediated Synapse Elimination After Stroke.

Background: Activating glutamatergic neurons in the ipsilesional motor cortex can promote functional recovery after stroke. However, the underlying molecular mechanisms remain unclear. Clarifying key molecular mechanisms involved in recovery could help understand the development of neuromodulation strategies after stroke.

GATv2EPI: Predicting Enhancer-Promoter Interactions with a Dynamic Graph Attention Network.

Background: The enhancer-promoter interaction (EPI) is a critical component of gene regulatory networks, playing a significant role in understanding the complexity of gene expression. Traditional EPI prediction methods focus on one-to-one interactions, neglecting more complex one-to-many and many-to-many patterns. To address this gap, we utilize graph neural networks to comprehensively explore all interaction patterns between enhancers and promoters, capturing complex regulatory relationships for more accurate predictions.

Estimation of Central Aortic Pressure Waveforms by Combination of a Meta-Learning Neural Network and a Physics-Driven Method.

The accurate non-invasive detection and estimation of central aortic pressure waveforms (CAPW) are crucial for reliable treatments of cardiovascular system diseases. But the accuracy and practicality of current estimation methods need to be improved. Our study combines a meta-learning neural network and a physics-driven method to accurately estimate CAPW based on personalized physiological indicators.

Hydrogen storage properties of TiFe-based composite with Ni addition.

This paper presents the preparation of the parental experimental alloy, featuring a standard composition of TiYZrFeNiMn, via the vacuum induction melting technique. Subsequently, the TiYZrFeNiMn alloy, with an addition of 2 wt% Ni, underwent mechanical ball milling to yield a TiFe-based composite for experimental purposes. The results of the experimental tests indicate that the composite alloy's phase composition comprises the TiFe primary phase, with a minor quantity of ZrMn phase segregated on the surface of the primary TiFe phase, as well as Ni phase.

Ordered Photoexfoliation for Polypseudorotaxane Nanosheets.

Two-dimensional layered structural materials exhibit a wide range of properties due to their ultrahigh specific surface area. However, achieving ordered exfoliation to obtain uniform two-dimensional structures remains challenging. In this study, we developed a supramolecular system by covalently bonding hexathiobenzene (HB) into β-cyclodextrin to create a light-responsive moiety, followed by coassembly with bipyridine and nickel ions to form a polypseudorotaxane (PR) system, which enables an light-induced exfoliation strategy for two-dimensional materials.

SERS-based simplified analysis of paraquat in poisoning cases: Bypassing complicated pretreatment with antioxidant sensor.

Applying antioxidant coating materials to prepare surface-enhanced Raman spectroscopy (SERS) sensing substrates can effectively enhance the sensitivity and stability for the analysis of molecules. In this study, we have leveraged SERS to develop an innovative sensor for the swift identification of Paraquat (PQ), enabling on-site detection of this herbicide. The newly devised sensor distinguishes itself through its exceptional oxidation resistance.

Tea consumption and cognitive health in Chinese older adults: A propensity score matching and weighting analysis.

Background: The association between tea consumption, especially different types, and cognitive function has not been adequately explored. This study aimed to investigate the associations of tea consumption, including status, frequency, and type, with cognitive function, considering selection bias.

Methods: We used data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2018(N = 8498).

Irregular seeds DEM parameters prediction based on 3D point cloud and GA-BP-GA optimization.

Due to the small and irregular shapes of vegetable seeds, modeling them is challenging, and the imprecision of physical parameters hinders the performance of vegetable seeders, impeding simulation development. In this study, seeds of cucumber, pepper, and tomato were seen as examples. A 3D point cloud reconstruction method based on Structure-from-Motion Multi-View Stereo (SfM-MVS) was employed to accurately extract 3D models of small and irregularly shaped seeds.

Diagnostic value of dual-layer spectral detector CT parameters for differentiating high- from low-grade bladder cancer.

Objectives: This study aimed to investigate the diagnostic value of spectral parameters of dual-layer spectral detector computed tomography (DLCT) in distinguishing between low- and high-grade bladder cancer (BCa).

Methods: This single-center retrospective study included pathologically confirmed BCa patients who underwent preoperative contrast-enhanced DLCT. Patients were divided into low- and high-grade groups based on pathology.

Tunable Multisoliton State Ultrafast Fiber Laser Based on NiSe and Generation of Vector Dual-Wavelength Solitons.

As a member of the chalcogenide family, NiSe exhibits a direct bandgap of 1.74 eV, making it a promising candidate for nonlinear optical devices. However, its potential in the near-infrared region of the telecommunication band has not been fully explored.