Publications by authors named "Summer Selinger"
Sublethal 6PPD-quinone exposure impairs swimming performance and aerobic metabolism in juvenile lake trout (Salvelinus namaycush).
Comp Biochem Physiol C Toxicol Pharmacol
March 2025
6PPD-quinone, an environmental oxidation product of the rubber tire antioxidant 6PPD, has recently gained recognition as a chemical of concern. Frequently detected in road runoff and surface waters, studies have reported this compound to cause acute lethality in several salmonid species at extremely low concentrations, including lake trout (Salvelinus namaycush; 24-h LC = 0.51 μg/L).
View Article and Find Full Text PDFN-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-quinone) is an environmental transformation product of the widely used rubber tire antioxidant, 6PPD. Found in stormwater runoff, 6PPD-quinone has been reported to cause acute lethality at ≤1 μg/L in salmonids like coho salmon, rainbow trout, and brook trout. Conversely, other species such as Arctic char and brown trout are insensitive, even when exposed to significantly greater concentrations (3.
View Article and Find Full Text PDFArticle Synopsis
- The contaminant 6PPD-Q, resulting from the oxidation of a tire antidegradant, is highly toxic to certain salmon species, while other fish show tolerance at higher concentrations.
- This research aimed to understand why some fish species react differently to 6PPD-Q by analyzing its metabolites in the bile of both sensitive and tolerant species.
- Findings revealed that tolerant fish had higher levels of a specific 6PPD-Q metabolite, indicating they may detoxify the compound more efficiently, suggesting that differing enzyme expressions could explain varying sensitivities.