An efficient 2-aminothiazolesalicylaldehyde fluorescent chemosensor for Fe ion detection and a potential inhibitor of NUDT5 signaling hormone for breast cancer cell and molecular keypad lock application.

Unlabelled: A novel thiazole phenol conjugate, 2-aminothiazolesalicylaldehyde (receptor1) was designed and synthesized for the first time through a single step process via Schiff base condensation reaction. The formation of receptor1 was confirmed by FTIR, C NMR, and H NMR. The IR spectra confirmed the presence of the aldimine formation.

Performance of 2-Hydroxy-1-Naphthaldehyde-2-Amino Thiazole as a Highly Selective Turn-on Fluorescent Chemosensor for Al(III) Ions Detection and Biological Applications.

The thiazole based Schiff base 2-hydroxy-1-naphthaldehyde-2-amino thiazole (receptor1) was synthesized through a single step process and characterized by spectroscopic and analytical techniques. The cation detecting ability of the receptor1 was explored by fluorescent spectroscopic methods. The receptor1 has recognized Al ions by a turn-on process over a panel of other potentially competing metal ions.