Advancing Green Chemistry in Antiviral Therapeutics: A Comprehensive Review.

Cytomegalovirus (CMV) is a prevalent virus across the world that belongs to the family Herpesviridae but remains dormant in the body unless the immune system is compromised. In addition, when the bacterium is compromised without any health risks, the infection spreads from one person to another person through body fluids, such as saliva, blood, etc. Ganciclovir is an anti- viral medication used in treating viral infections, especially in the treatment of CMV in people with acquired immune deficiency syndrome and immunity at risk.

Advanced Targeted Drug Delivery of Bioactive Agents Fortified with Graft Chitosan in Management of Cancer: A Review.

Cancer is characterized by the uncontrolled proliferation and spread of abnormal cells in the body, resulting in the development of tumors or clusters of irregular cells. The factors contributing to cancer are intricate, involving a combination of genetic, environmental, and lifestyle elements. Risk factors for cancer include the use of nicotine, excessive alcohol consumption, exposure to radiation or specific chemicals, and a family history of the disease.

Computational investigation of four isoquinoline alkaloids against polycystic ovarian syndrome.

Hyperandrogenism, insulin resistance, and estrogen dominance are the prime defining traits of women with polycystic ovarian syndrome which disrupts hormonal, adrenal, or ovarian functions resulting in impaired folliculogenesis and excess androgen production. The purpose of this study is to identify an appropriate bioactive antagonistic ligand from isoquinoline alkaloids [palmatine (PAL), jatrorrhizine (JAT), magnoflorine (MAG) and berberine (BBR)] from stems of . Phytocomponents inhibit/prevent androgenic, estrogenic, and steroidogenic receptors, insulin binding, and resultant hyperandrogenism.

Automated semantic lung segmentation in chest CT images using deep neural network.

Lung segmentation algorithms play a significant role in segmenting theinfected regions in the lungs. This work aims to develop a computationally efficient and robust deep learning model for lung segmentation using chest computed tomography (CT) images with DeepLabV3 + networks for two-class (background and lung field) and four-class (ground-glass opacities, background, consolidation, and lung field). In this work, we investigate the performance of the DeepLabV3 + network with five pretrained networks: Xception, ResNet-18, Inception-ResNet-v2, MobileNet-v2 and ResNet-50.

Automated Detection of Infection in Diabetic Foot Ulcer Images Using Convolutional Neural Network.

A bacterial or bone infection in the feet causes diabetic foot infection (DFI), which results in reddish skin in the wound and surrounding area. DFI is the most prevalent and dangerous type of diabetic mellitus. It will mainly occur in people with heart disease, renal illness, or eye disease.

Analysis of a solar still with photovoltaic modules and electrical heater - Energy and exergy approach.

The availability of drinkable water, along with food and air, is a fundamental human necessity. Because of the presence of higher amounts of salt and pollution, direct use of water from sources such as lakes, sea, rivers, and subsurface water reservoirs is not normally suggested. Solar is still a basic technology that can use solar energy to transform accessible waste or brackish water into drinkable water.

Gastrointestinal Tract Disease Classification from Wireless Endoscopy Images Using Pretrained Deep Learning Model.

Wireless capsule endoscopy is a noninvasive wireless imaging technology that becomes increasingly popular in recent years. One of the major drawbacks of this technology is that it generates a large number of photos that must be analyzed by medical personnel, which takes time. Various research groups have proposed different image processing and machine learning techniques to classify gastrointestinal tract diseases in recent years.

Diagnosis of Cervical Cancer based on Ensemble Deep Learning Network using Colposcopy Images.

Traditional screening of cervical cancer type classification majorly depends on the pathologist's experience, which also has less accuracy. Colposcopy is a critical component of cervical cancer prevention. In conjunction with precancer screening and treatment, colposcopy has played an essential role in lowering the incidence and mortality from cervical cancer over the last 50 years.

A novel Smart Routing Protocol for remote health monitoring in Medical Wireless Networks.

In a Medical Wireless Network (MWN), sensors constantly monitor patient's physiological condition and movement. Inter-MWN communications are set up between the Patient Server and one or more Centralized Coordinators. However, MWNs require protocols with little energy consumption and the self-organizing attribute perceived in ad-hoc networks.

Anticancer activity of Sargassum wightii Greville on Dalton's ascitic lymphoma.

Aim: Sargassum wightii Greville is a marine brown alga belonging to the Sargassaceae family which has about 200 species. The ethanolic extract of the whole dry plant powder contained numerous phytoconstituents, including flavonoids. The study was focused on the anticancer activity of Sargassum wightii in mice.

Neuroprotective and antioxidant potential of terpenoid fraction from Hygrophila auriculata against transient global cerebral ischemia in rats.

Context: The plant Hygrophila auriculata (K. Schum) Heine. (Acanthaceae) is widely used in the Indian System of Medicine as "Rasayana" for treating brain and liver diseases.

Colorimetric method for the estimation of escitalopram oxalate in tablet dosage form.

A colorimetric method for the analysis of escitalopram oxalate in pure form and in tablets has been developed based on the formation of chloroform soluble ion associates with bromocresol green acidic dye. The extract of ion associates exhibited absorption maxima at 417 nm obeying Beer's law in the range of 2-10 µg/ml. The method is simple, precise and accurate with recovery of 98-102% and does not require any separation of soluble excipients from tablet dosage form.

Antitumor and cytotoxic effects of Phyllanthus polyphyllus on Ehrlich ascites carcinoma and human cancer cell lines.

To evaluate the antitumor and cytotoxic activity of methanol extract of Phyllanthus polyphyllus (MPP) in mice and human cancer cell lines, the antitumor activity of MPP was evaluated against an Ehrlich ascites carcinoma (EAC) tumor model. The activity was assessed using survival time, hematological studies, lipid peroxidation (LPO), antioxidant enzymes such as superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx), glutathione S-transferase (GST), solid tumor mass, and short-term in vitro cytotoxicity. The cytotoxic activity of MPP was evaluated using human breast cancer (MCF7), colon cancer (HT29), and liver cancer (HepG2) cell lines Oral administration of MPP (200 and 300 mg/kg) increased the survival time and significantly reduced the solid tumor volume in a dose-dependent manner.