Endoscopic optical coherence tomography (OCT) possesses the capability to non-invasively image internal lumens; however, it is susceptible to saturation artifacts arising from robust reflective structures. In this study, we introduce an innovative deep learning network, ATN-Res2Unet, designed to mitigate saturation artifacts in endoscopic OCT images. This is achieved through the integration of multi-scale perception, multi-attention mechanisms, and frequency domain filters.
View Article and Find Full Text PDFSignificance: In the photoacoustic (PA) technique, the laser irradiation in the time domain (i.e., laser pulse duration) governs the characteristics of PA imaging-it plays a crucial role in the optical-acoustic interaction, the generation of PA signals, and the PA imaging performance.
View Article and Find Full Text PDFOptical coherence tomography (OCT) is an imaging modality that acquires high-resolution cross-sectional images of living tissues and it has become the standard in ophthalmological diagnoses. However, most quantitative morphological measurements are based on the raw OCT images which are distorted by several mechanisms such as the refraction of probe light in the sample and the scan geometries and thus the analysis of the raw OCT images inevitably induced calculation errors. In this paper, based on Fermat's principle and the concept of inverse light tracing, image distortions due to refraction occurred at tissue boundaries in the whole-eye OCT imaging of mouse by telecentric scanning were corrected.
View Article and Find Full Text PDFSegmenting liver from CT images is the first step for doctors to diagnose a patient's disease. Processing medical images with deep learning models has become a current research trend. Although it can automate segmenting region of interest of medical images, the inability to achieve the required segmentation accuracy is an urgent problem to be solved.
View Article and Find Full Text PDFOptical coherence tomography angiography (OCTA) has been widely used in clinical fields because of its noninvasive, high-resolution qualities. Accurate vessel segmentation on OCTA images plays an important role in disease diagnosis. Most deep learning methods are based on region segmentation, which may lead to inaccurate segmentation for the extremely complex curve structure of retinal vessels.
View Article and Find Full Text PDFAn increasing number of experiments had verified that miRNA expression is related to human diseases. The miRNA expression profile may be an indicator of clinical diagnosis and provides a new direction for the prevention and treatment of complex diseases. In this work, we present a weighted voting-based model for predicting miRNA-disease association (WVMDA).
View Article and Find Full Text PDFApple is one of the most economically important horticultural fruit crops worldwide. It is critical to gain insights into fruit ripening and softening to improve apple fruit quality and extend shelf life. In this study, forward and reverse suppression subtractive hybridization libraries were generated from 'Taishanzaoxia' apple fruits sampled around the ethylene climacteric to isolate ripening- and softening-related genes.
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