Publications by authors named "Sumesh Kumar Dash"
Introduction: Acinetobacter baumanii (AB) is a bacterium of concern in the hospital setup due to its ability to thrive in unfavorable conditions and the rapid emergence of antibiotic resistance. Carbapenem resistance in this organism is disheartening, further clouded by the emergence of colistin resistance.
Aim: The present prospective study aims to note the epidemiology, molecular profile, and clinical outcome of patients with colistin resistance AB infections in a multispecialty tertiary care setup in Odisha, Eastern India.
Article Synopsis
- - The study addresses the rising issue of antibiotic resistance in bacteria, specifically focusing on carbapenem-resistant Enterobacterales (CRE), CRAB, and CRPA, which has led to the use of older antibiotics like colistin, despite emerging resistance to it.
- - Researchers evaluated colistin susceptibility in 6,013 carbapenem-resistant isolates using three methods: broth microdilution (BMD), colistin broth disc elution (CBDE), and Vitek two, comparing their effectiveness based on various accuracy metrics (e.g., sensitivity and specificity).
- - Results indicated a colistin resistance rate of 12.9% among the isolates, with Vitek two showing high sensitivity (78.2–84.