Publications by authors named "Sumer Baroud"

Acne vulgaris, the most common form of acne, is characterized by a mixed eruption of inflammatory and noninflammatory skin lesions primarily affecting the face, upper arms, and trunk. The pathogenesis of acne is multifactorial and includes abnormal keratinization and plugging of the hair follicles, increased sebum production, proliferation and activation of (; formerly , ), and finally inflammation. Recent studies have found that cannabidiol (CBD) may be beneficial in the treatment of acne.

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Article Synopsis
  • Abnormal mosaicism refers to an individual having more than one genetic type in their cells from the same zygote, which can lead to diseases, including certain types of acne.
  • Acne is a chronic condition often linked to hormonal and inflammatory processes and is associated with various systemic disorders, such as congenital adrenal hyperplasia and polycystic ovarian syndrome.
  • The review discusses cutaneous mosaicism and its connection to acne syndromes, highlighting the role of specific germline mutations related to conditions like Apert syndrome and nevus comedonicus that can also present with acneiform lesions.
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Infantile systemic hyalinosis (ISH) is a rare, autosomal recessive disorder characterized by widespread abnormal growth of hyalinized fibrous tissue in skin and mucosae. The typical clinical picture consists of the development of joint contractures, skin lesions, and severe, chronic pain. We report the case of a 2-year-old Pakistani girl, who presented to our clinic with papulonodular lesions, gingival hyperplasia, hypotonia, and joint contractures.

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Background: There is growing evidence that (certain) hidradenitis suppurativa (HS) comorbidities comprise syndromes including HS as a key cutaneous manifestation. These apparently autoinflammatory syndromes and their diagnostic delay might have detrimental effects on affected patients.

Methods: A systematic review was performed on the databases MEDLINE, EMBASE, and CENTRAL utilizing a standardized extraction form according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

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