Publications by authors named "Sumedha Kapre"
Exosomes or so-called natural nanoparticles have recently shown enormous potential for targeted drug delivery systems. Several studies have reported that exosomes as advanced drug delivery platforms offer efficient targeting of chemotherapeutics compared to individual polymeric nanoparticles or liposomes. Taking structural constituents of exosomes, , proteins, nucleic acids, and lipids, into consideration, exosomes are the most promising carriers as genetic messengers and for treating genetic deficiencies or tumor progression.
View Article and Find Full Text PDFImmunotherapy is a rapidly advancing field of research in the treatment of conditions such as cancer and autoimmunity. Nanomaterials can be designed for immune system manipulation, with precise targeted delivery and improved immunomodulatory efficacy. Here, we elaborate on various strategies using nanomaterials, including liposomes, polymers, and inorganic NPs, and discuss their detailed design intricacies, mechanisms, and applications, including the current regulatory issues.
View Article and Find Full Text PDFArticle Synopsis
- The tumor microenvironment (TME) is the area around cancer cells that helps tumors grow and can make treatment harder by blocking drugs and hiding the tumors from the immune system.
- New therapies are being developed to target the TME, including methods to change the environment around the tumor and to better use the immune system to fight cancer.
- Understanding the complex TME is important because it can help scientists create better treatments that work for different patients, and it requires teamwork and new technologies to really figure it out.