[The problem of homologous blood in transfusiology and its solution].

In cardiosurgery conducted in this country and abroad the development of homologous blood syndrome was observed. Its frequency comprises up to 2.5%, according to the authors' data.

[Phenomenon of indirect isoserological incompatibility in experimental transfusion research and its clinical significance].

It has been established in experiments on dogs exposed to blood transfusions that if the animals are screened according to the cross-matching testing system and show as a result the lack of red blood cell agglutination, this does not provide evidence in favour of their complete isoserological compatibility. To confirm whether the animals are compatible, it is required to carry out 7 to 8 tests with other species. If the tests reveal red blood cell agglutination, blood transfusion is characterized by demonstrable isoserological incompatibility and the recipient dies.

[Potentials of a noninvasive method for studying volumetric cerebral blood flow in mitral stenosis and following its surgical correction].

The volumetric parameters of the cerebral blood flow were studied in 15 patients who had undergone comissurotomy, using the comprehensive rheographic method including tetrapolar rheoencephalography and transthoracic rheography. The non-invasive method makes it possible to determine the minute's volume of the brain circulation as well as its ratio to cardiac output. The results obtained point to a positive time-course of the brain blood flow following the surgical correction of mitral stenosis.

[Effect of artificial hypothermia on cardio- and hemodynamics].

Three series of dog experiments were carried out to study the effect of artificial hypothermia on the cardiac activity and main hemodynamic parameters. In the first series (120 experiments), the dogs were exposed to immersion cooling. In 104 experiments of this series, the whole animal body was cooled to 18-20 degrees C whereas in 16 experiments with the same rate of body hypothermia, selective heart normothermia was maintained by means of an original method of indirect cardiosynchronized warm blood perfusion into the coronary artery.

[Acute cardiac insufficiency and water-electrolyte metabolism in the postoperative period in congenital heart defects].

The study was conducted in 58 patients with congenital heart diseases. Preoperative cardiac insufficiency in patients with congenital heart diseases was shown to favour a complicated postoperative course which, in turn, is accompanied by alterations in the water-electrolyte metabolism. The development of cellular hyperhydration in patients with congenital heart diseases depends on the severity of the postoperative course and is its characteristic reflection.

[Change in cerebral bioelectric activity during whole body hypothermia and regional cooling of the head].

Two series of experiments were conducted on dogs. In the first series of experiments dogs were subjected to deep hypothermia with an external chilling of the organism; in the second series-to the isolated deep hypothermia of the head with the maintenance of normothermia in the organism. Bioelectrical activity of the brain and circulation minute volume were recorded in the animals of both series.