Synopsis of recent research by authors named "Sumati Hasani"
Sumati Hasani's research primarily focuses on the metabolic adaptations and signaling pathways involved in colon cancer, particularly examining the role of mitochondrial dynamics and nutrient uptake in cancer progression and treatment resistance.
Recent findings revealed that inhibition of mitochondrial fission can activate glycogen synthesis, suggesting potential therapeutic strategies to enhance cell survival in colon cancer.
Additionally, Hasani's work highlights the interplay between endoplasmic reticulum stress, protein phosphatase PHLPP, and chemoresistance, providing insights into the mechanisms of tumor resilience and potential avenues for targeted therapies.