Publications by authors named "Suman Rani"

Article Synopsis
  • Osteoarthritis, particularly Knee Osteoarthritis (KOA), significantly impacts mobility and quality of life due to pain and stiffness, and can be caused by factors like aging and obesity.
  • The study uses a specialized 12-layer Convolutional Neural Network (CNN) to analyze data from the Osteoarthritis Initiative (OAI) for classifying the severity of KOA through medical image processing.
  • The CNN model achieves a high accuracy of 92.3% for binary classification and 78.4% for multiclassification of KOA, suggesting potential for improved detection methods in the future.
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The imperative development of a cutting-edge environmental gas sensor is essential to proficiently monitor and detect hazardous gases, ensuring comprehensive safety and awareness. Nanostructures developed from metal oxides are emerging as promising candidates for achieving superior performance in gas sensors. NO is one of the toxic gases that affects people as well as the environment so its detection is crucial.

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Nineteen heterocyclic chalcones were synthesized from 4-acetyl-5-methylquinolylpyrazole and heteroaryl (imidazole, pyrazole, thiophene, indole and triazole) aldehydes and were screened in vitro using four tumor cell lines for their cytotoxic capability and for antimicrobial activity. The chalcone 5b exhibited the highest activity with IC values 2.14 μM against colon (HCT-116) and 5.

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L-alanine possesses extensive physiological functionality and tremendous pharmacological significance, therefore could be considered as potential ingredient for food, pharmaceutical, and personal care products. However, therapeutic properties of L-alanine still need to be addressed in detail to further strengthen its utilization as a viable ingredient for developing natural therapeutics with minimum side effects. Thus, the present study was aimed to explore the anticipated therapeutic potential of L-alanine, produced microbially using a lactic acid bacterial strain Pediococcus acidilactici BD16 (alaD) expressing L-alanine dehydrogenase enzyme.

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The fission yeast, Schizosaccharomyces pombe, is an excellent model for basic research but is not useful for commercial scale protein expression due to lack of strong expression vectors. Earlier, we showed that the lsd90 promoter elicited significantly greater GFP expression level than the adh1 and nmt1 promoters, albeit in different vector backbones. Here, we have systematically investigated the contribution of selectable markers, LEU2 and URA3m to GFP expression: while LEU2 elicited very low expression, the URA3m gene, with truncated promoter, elicited much greater GFP expression level with all promoters.

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In the present investigation, a fresh water green algae spirogyra spp. was used as an inexpensive and efficient biosorbent for Cr(III) removal from aqueous solution. The algal biomass was treated with 0.

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