Evaluation of the anti-hyperlipidemic effects of in high fat diet fed rats: Studies with two combinations.

Background: Hyperlipidemia is one of the major risk factors for coronary heart disease and stroke. , a polyherbal Ayurvedic formulation made from dried fruits of ( Retz.), ( Roxb.

Folic acid conjugated FeO magnetic nanoparticles for targeted delivery of doxorubicin.

The interfacial engineering of magnetic nanoparticles (MNPs) with specific functional groups or targeting ligands is important for their in vivo applications. We report here the preparation and characterization of bifunctional magnetic nanoparticles (BMNPs) which contain a carboxylic moiety for drug binding and an amine moiety for folate mediated drug targeting. BMNPs were prepared by introducing bioactive cysteine molecules onto the surface of undecenoic acid coated FeO magnetic nanoparticles (UMNPs) via a thiol-ene click reaction and then, folic acid was conjugated with these BMNPs through an EDC-NHS coupling reaction.

Making sense of Brownian motion: colloid characterization by dynamic light scattering.

Dynamic light scattering (DLS) has evolved as a fast, convenient tool for particle size analysis of noninteracting spherical colloids. In this historical review, we discuss the basic principle, data analysis, and important precautions to be taken while analyzing colloids using DLS. The effect of particle interaction, polydispersity, anisotropy, light absorption, and so forth, on measured diffusion coefficient is discussed.

Polyaniline shell cross-linked Fe3O4 magnetic nanoparticles for heat activated killing of cancer cells.

Superparamagnetic Fe3O4 nanoparticles are appealing materials for heat activated killing of cancer cells. Here, we report a novel method to enhance the heat activated killing of cancer cells under an AC magnetic field (AMF) by introducing a polyaniline impregnated shell onto the surface of Fe3O4 nanoparticles. These polyaniline shell cross-linked magnetic nanoparticles (PSMN) were prepared by in situ polymerization of aniline hydrochloride on the surface of carboxyl PEGylated Fe3O4 nanoparticles.