Specific heterozygous variants in MGP lead to endoplasmic reticulum stress and cause spondyloepiphyseal dysplasia.

Matrix Gla protein (MGP) is a vitamin K-dependent post-translationally modified protein, highly expressed in vascular and cartilaginous tissues. It is a potent inhibitor of extracellular matrix mineralization. Biallelic loss-of-function variants in the MGP gene cause Keutel syndrome, an autosomal recessive disorder characterized by widespread calcification of various cartilaginous tissues and skeletal and vascular anomalies.

Oral Health Knowledge, Attitudes, and Behaviors Among University Students in Jeddah, Saudi Arabia.

Purpose: This study aimed to evaluate oral health knowledge, attitudes, and behaviors among a sample of senior students at King Abdulaziz University (KAU), and to assess differences among these factors between genders.

Methods: A total of 1177 senior university students at KAU were included in this cross-sectional study. Participants were selected by stratified random sampling.