The Impact of Angiotensin Receptor-Neprilysin Inhibitors on Arrhythmias in Patients with Heart Failure: A Systematic Review and Meta-analysis.

Angiotensin receptor-neprilysin inhibitor (ARNI) use has become increasingly popular. Current guidelines recommend using ARNI therapy for heart failure with reduced (HFrEF) and preserved ejection fraction (HFpEF). As therapies become more widely available, heart failure-associated burdens such as ventricular arrhythmias and sudden cardiac death (SCD) will become increasingly prevalent.

A Shocking Discovery: Apical Thrombus Formation Post-Cardiac Resynchronization Therapy Placement.

• CRT-D is beneficial for patients in systolic heart failure with dyssynchrony. • Complications after CRT-D placement can arise due to changes post–myocardial infarction. • Apical thrombus can develop in a predisposed area in the left ventricle.

Atrial fibrillation following cardiac surgery: established and emerging strategies of prevention.

More than 250,000 patients undergo cardiac surgery every year. Although advances in surgical techniques have reduced the peri-operative morbidity and mortality in these patients, atrial fibrillation persists to commonly occur following these surgeries. Traditional therapies have reduced their occurrence; however there are still a significant number of patients who develop this complication.

Atrial fibrillation--advances in drug therapy.

The prevalence of atrial fibrillation (AF) continues to increase worldwide. It is projected that by 2050, between 5 and 15 million Americans will have AF. Such predictions necessitate new advances in drug therapy.

Mechanisms of organized left atrial tachycardias occurring after pulmonary vein isolation.

Background: A proarrhythmic consequence of pulmonary vein (PV) isolation can be a recurrent organized left atrial (LA) tachycardia after ablation. This arrhythmia is frequently referred to as "left atrial flutter," but the mechanism and best ablation strategy have not been determined.

Methods And Results: Isolation of arrhythmogenic PVs was initially performed by segmental ostial PV ablation guided by a circular mapping catheter in 341 patients.