Publications by authors named "Sultan O Alolayan"
Bilastine, a new second generation antihistaminic drug, has been widely used for relieving symptoms of allergic rhinitis and urticaria without a sedative effect. A simple, cost-effective, and highly sensitive fluorimetric method was developed for the estimation of bilastine in human plasma, in addition to its pure state and tablets. The suggested method depended on binary complex formation of eosin with bilastine in a buffered medium at pH 4.
View Article and Find Full Text PDF: Chronic kidney disease (CKD) poses a significant risk for end-stage renal disease (ESRD), cardiovascular diseases, and premature death. The study aims to assess CKD knowledge and predictive variables among the general public. A cross-sectional study was conducted among the general public in Al Medina Al-Munawara, Saudi Arabia, utilizing a 21-item questionnaire-based approach over a 4-month period from January 2023 to April 2023.
View Article and Find Full Text PDFObjective: To investigate public uptake, attitudes and the safety of the first and second doses of COVID-19 vaccination.
Methods: This was a cross-sectional web-based survey study. A self-administered questionnaire was prepared from a literature search and information about COVID-19 available at various resources.
Article Synopsis
- The study assessed the pharmaceutical and vaccine supply chain in Pakistan, focusing on its structure, processes, outcomes, and barriers.
- Data was collected through semi-structured interviews with stakeholders, highlighting issues such as inadequate standard operating procedures at community pharmacies and challenges in inventory management.
- Key areas for improvement include better forecasting and inventory control, enhanced training, and further integration among stakeholders to strengthen the supply chain system.
COVID-19 is caused by coronavirus (SARS-CoV-2) is a worldwide health crisis. This severe acute respiratory syndrome was declared an outbreak after the first case was reported in Wuhan, the capital city of Hubei Province in China. On March 11th, 2020, the World Health Organization (WHO) declared it as a pandemic.
View Article and Find Full Text PDFMarine environment has been identified as a huge reservoir of novel biometabolites that are beneficial for medical treatments, as well as improving human health and well-being. Sponges have been highlighted as one of the most interesting phyla as new metabolites producers. Thiele (Thorectidae) is a wealth pool of various classes of sesquiterpenes, including hydroquinones, quinones, and tetronic acid derivatives.
View Article and Find Full Text PDFArticle Synopsis
- Irrational self-medication (SM) is linked to poor health outcomes and can worsen existing health issues, highlighting the importance of responsible SM practices.
- In a study of 611 community residents, 52.9% reported practicing SM, mainly for minor ailments like headaches and pain, using medications such as painkillers and herbal remedies.
- Reasons for SM included previous experiences and the convenience of avoiding healthcare visits; however, many participants recognized the risks of inappropriate SM, with a strong interest in learning about safe practices and returning unused medications.
Objective: The aim of this study was to validate the Arabic version of General Medication Adherence Scale (GMAS) in Sudanese patients with type 2 diabetes mellitus (T2DM).
Methods: A 3-month cross-sectional study was conducted among patients with T2DM at Al-Daraja Health Center, located in Wad Medani, Sudan. A convenient sample of patients was selected, and the study sample size was calculated using the item response ratio.
Article Synopsis
- Vitamin D plays a crucial role in both innate and adaptive immunity, potentially influencing the severity and management of acute asthma episodes.
- A study measured serum levels of various vitamin D forms in 113 participants (73 asthmatics and 40 healthy controls), finding that asthmatic patients had significantly lower vitamin D levels compared to controls.
- Strong negative correlations were observed between vitamin D levels and asthma severity markers, suggesting that vitamin D deficiency may contribute to worse asthma control and severity.
Objectives: Pharmacoeconomics and health economics in general is a new field that is still developing and emerging, not only in Saudi Arabia but all over the world. The objective of this study is to collect all published cost-effectiveness analysis (CEA) studies conducted based on Saudi settings and to evaluate their reporting quality.
Methods: We used PRISMA guidelines to search for all English-language CEAs conducted in Saudi Arabia in 3 databases: Medline, Embase, and Scopus.
Protective effect of metformin on rat diabetic retinopathy involves suppression of toll-like receptor 4/nuclear factor-k B expression and glutamate excitotoxicity.
Int Immunopharmacol
January 2021
Microvascular complications of diabetes mellitus are progressively significant reasons for mortality. Metformin (MET) is considered as the first-line therapy for type 2 diabetes patients, and may be especially beneficial in cases of diabetic retinopathy although the precise mechanisms of MET action are not fully elucidated. The current study was designed to inspect the antioxidant and modulatory actions of MET on DRET in streptozotocin-induced diabetic rats.
View Article and Find Full Text PDFPurpose: The study aimed to translate and validate the Arabic version of General Medication Adherence Scale (GMAS) in Saudi patients with chronic diseases.
Methods: A multi-center cross sectional study was conducted for a month in out-patient wards of hospitals in Khobar, Dammam, Makkah, and Madinah, Saudi Arabia. Patients were randomly selected from a registered patient pools at hospitals and the item-subject ratio was kept at 1:20.