Introduction: Appendiceal neoplasms (ANs) are uncommon, representing less than 1% of all gastrointestinal tumors. They are most often discovered incidentally during appendectomies performed for suspected acute appendicitis. Recent studies have reported an increase in the incidence of AN.
View Article and Find Full Text PDFIntroduction Errors occur in the laboratory at any level of the testing process. Recognizing these errors may cause patient distress by delaying diagnosis and management until results are released. This study aims to assess preanalytical errors in the laboratory and suggests methods to prevent them to improve accuracy and efficiency in the hematology department of a tertiary care hospital.
View Article and Find Full Text PDFHailey-Hailey disease (HHD) is a rare autosomal dominant chronic blistering disorder. It presents with eruption of small vesicles, erosions, and crusted plaques frequently in the intertriginous areas. Family history is present in some cases.
View Article and Find Full Text PDFThymoma is a rare, primary neoplasm of the thymus gland, commonly presenting in adults and associated with autoimmune diseases, most commonly myasthenia gravis (MG). Despite its generally indolent behavior, the variability in clinical presentation and potential for malignancy necessitates detailed evaluation and management. In this report, we present two cases: a 41-year-old male and a 39-year-old female, both of whom presented with a mediastinal mass with symptoms of myasthenia.
View Article and Find Full Text PDFBeta-thalassemia is one of the most common inherited hematological diseases caused by more than 350 mutations in the β-globin gene (HBB). Beta-thalassemia carrier or trait is associated with defects in one allele of the HBB gene. The majority of beta-thalassemia trait cases remain concealed in society and remain unnoticed as they are mostly asymptomatic or present with mild symptoms of anemia.
View Article and Find Full Text PDFIntroduction And Aim: Tumor budding is a distinctive phenomenon which involves the presence of small clusters or individual cancer cells at the invasive front of tumors. Tumor budding has garnered attention due to its potential implications for prognosis, treatment strategies, and our understanding of cancer progression. Our aim is to study the distribution of tumor buds and its scoring in patients with infiltrating breast carcinoma and to associate with other histopathological parameters like the size of the tumor, its grade, lymphovascular invasion, and lymph node metastasis.
View Article and Find Full Text PDFMetaplastic breast carcinoma (MBC) is a rare and aggressive subtype of breast cancer characterized by the presence of both epithelial and mesenchymal components within the tumor. Its clinical and radiological appearance is comparable to other types of breast cancer, but it grows rapidly. The diagnosis of metaplastic carcinoma is largely based on the epithelial origin of the cells confirmed by immunohistochemistry (IHC).
View Article and Find Full Text PDFIntroduction Pre-analytical errors in cytology laboratories can significantly impact the accuracy of diagnostic results and turnaround times, ultimately affecting patient care. This article presents an evaluation of pre-analytical errors and proposes fostering strategies to enhance accuracy and efficiency in the cytology laboratory of a tertiary care hospital. The background discusses the importance of pre-analytical processes in ensuring reliable cytological diagnoses and the common errors encountered in specimen collection, handling, and transportation.
View Article and Find Full Text PDFChondroid syringoma is a rare mixed tumour of the skin. It was first described by Hirsch and Helwig. The tumour is composed of a proliferation of epithelial cells present in a myxoid and chondroid matrix.
View Article and Find Full Text PDFCavernous hemangiomas are composed of dilated vessels which are filled with blood. Their common sites of occurrence include the skin, liver and the superficial and the deep soft tissues. We are presenting a rare case of cavernous hemangioma of the spinal cord.
View Article and Find Full Text PDFEpidermoid cysts of the ovary are rare benign lesions and they are usually an incidental finding in hysterectomy specimens. We are presenting the largest reported case of an epidermoid cyst of the ovary which measured 17x10x10 cm, in a 50 year old lady with a preoperative diagnosis of a fibroid uterus.
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