The prestige target selectivity and imaging depth of optical-resolution photoacoustic microscope (OR-PAM) have gained attentions to enable advanced intra-cellular visualizations. However, the broad-band nature of photoacoustic signals is prone to noise and artifacts caused by the inefficient light-to-pressure translation, resulting in poor image quality. The present study foresees application of singular value decomposition (SVD) to effectively extract the photoacoustic signals from these noise and artifacts.
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December 2023
We address the problem of limited temporal resolution in optical-resolution microscopy (OR-PAM) for cellular imaging by undersampling and reconstruction. A curvelet transform method in a compressed sensing framework (CS-CVT) was devised to specifically reconstruct the boundary and separability of cell objects in an image. The performance of the CS-CVT approach was justified by comparisons with the natural neighbor interpolation (NNI) followed by smoothing filters on various imaging objects.
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