An upgraded 2D nanosheet-based FRET biosensor: insights into avoiding background and eliminating effects of background fluctuations.

We demonstrated a new class of 2D nanosheet-based FRET biosensor utilizing vertically oriented MoS nanosheets on a magnetic nanocarrier. Compared with the non-separated biosensor under identical conditions, this upgraded one can avoid the background signal of the system and eliminate the effects of background fluctuations, which produces more excellent detection methods

Controlling the ligands of CdZnTe quantum dots to design a super simple ratiometric fluorescence nanosensor for silver ion detection.

A super simple ratiometric fluorescence nanosensor has been fabricated by controlling the ligands of CdZnTe quantum dots (QDs), allowing the sensitive and visual detection of silver ions (Ag). The green-emitting L-cysteine-protected CdZnTe QDs (Lcys-CdZnTe QDs) had a specific response to Ag and were used as the reporting probe, while the red-emitting -acetyl-L-cysteine-protected CdZnTe QDs (NAC-CdZnTe QDs) showed no obvious response to all tested metal ions and were selected as the reference probe. Simply mixing them without any encapsulated synthesis ultimately produced a time-saving, low-cost detection method, allowing the sensitive and visual detection of Ag in samples.