A plasmonic biosensor pre-diagnostic tool for Familial Mediterranean Fever.

Familial Mediterranean Fever (FMF) is an autosomal recessive genetic disorder, primarily observed in populations around the Mediterranean Sea, linked to MEFV gene mutations. These mutations disrupt inflammatory responses, increasing pyrin-protein production. Traditional diagnosis relies on clinical symptoms, family history, acute phase reactants, and excluding similar syndromes with MEFV testing, which is expensive and often inconclusive due to heterozygous mutations.

Tire Rubber Based Microplastic Particles Cause Adverse on Quality Parameters of Rainbow Trout Sperm Cells.

In the present study, we aimed to determine the parameters of oxidative stress markers, motility and kinematics of rainbow trout (Oncorhynchus mykiss) sperm cells exposed to different doses (0.001, 0.01, 0.

Synthesis of Cyclodextrin-Based Multifunctional Biocompatible Hydrogels and Their Use in the Prevention of Intrauterine Adhesions (Asherman's Syndrome) after Surgical Injury.

Asherman's syndrome, which can occur during the regeneration of damaged uterine tissue after surgical interventions, is a significant health problem in women. This study aimed to acquire and characterize cyclodextrin-based hydrogels, which can be used to prevent Asherman's syndrome, and investigate their effectiveness with biomedical applications. A series of hydrogels were synthesized from the cross-linking of β-cyclodextrin and different polyphenols with epoxy-functional PEG.

Preparation of pyridoxine-based polyurethane modified sensors and their use in simultaneous determination of Cu(II) - Co(II) ions.

In this study, pyridoxine-based polyurethane-modified electrodes were prepared to simultaneously and sensitively measure copper (Cu(II)) and cobalt (Co(II)) ions in complex matrix samples. For the production of the electrodes, firstly, the synthesis of pyridoxine-based polyurethane structures was carried out. In these syntheses, the polymer structure was diversified by using different isocyanates.

Effects of Yttrium Doping on Erbium-Based Hydroxyapatites: Theoretical and Experimental Study.

This is the first investigation of yttrium (Y) and erbium (Er) co-doped hydroxyapatite (HAp) structures, conducted using theoretical and experimental procedures. By using a wet chemical method, the materials were synthesized by varying the concentration of Y amounts of 0.13, 0.

Fast Curing Multifunctional Tissue Adhesives of Sericin-Based Polyurethane-Acrylates for Sternal Closure.

The use of wire cerclage after sternal closure is the standard method because of its rigidity and strength. Despite this, they have many disadvantages such as tissue trauma, operator-induced failures, and the risk of infection. To avoid complications during sternotomy and promote tissue regeneration, tissue adhesives should be used in post-surgical treatment.

Chemistry and engineering of brush type polymers: Perspective towards tissue engineering.

In tissue engineering, it is imperative to control the behaviour of cells/stem cells, such as adhesion, proliferation, propagation, motility, and differentiation for tissue regeneration. Surfaces that allow cells to behave in this way are critical as support materials in tissue engineering. Among these surfaces, brush-type polymers have an important potential for tissue engineering and biomedical applications.

The Cytotoxicity, DNA Fragmentation, and Decreasing Velocity Induced By Chromium(III) Oxide on Rainbow Trout Spermatozoa.

The present study aimed to determine the cytotoxicity of chromium(III) oxide micro particles (CrO-Ps) in rainbow trout (Oncorhynchus mykiss) spermatozoa. Firstly, CrO-Ps were synthesized and structurally characterized the surface, morphological for particle size and thermal properties. In addition, its structural and elemental purity was determined using energy-dispersive X-ray (EDX) spectrum and elemental maps.

Interaction of nickel ferrite nanoparticles with nucleic acids.

In this article, we introduced an electrochemical biosensor employing graphite electrodes (GE) decorated with Nickel ferrite (NiFeO) nanoparticles for nucleic acid detection. NiFeO nanoparticles in a narrow size distribution were synthesized with co-precipitation technique. Their chemical and crystallographic properties were characterized with FTIR and X-ray spectroscopies.

Photocrosslinkable gelatin/collagen based bioinspired polyurethane-acrylate bone adhesives with biocompatibility and biodegradability.

Hard or soft tissue adhesives have been presented as a promising candidate to replace traditional wound closure methods. However, there are mechanical strength problems in biological adhesives and biocompatibility problems in synthetic-based adhesives. At this point, we aimed to remove all these disadvantages and produce a single adhesive that contains all the necessary features and acrylate functionalized UV-curable polyurethane formulations were produced with high crosslink density, high adhesion strength, biocompatibility and injectable property for easy application as potential biomedical adhesives.

Determination of characterization, antibacterial and drug release properties of POSS-based film synthesized with sol-gel technique.

In the study, antibacterial film synthesis was aimed using sol-gel technique from POSS structure with various functional groups. For this purpose, antibacterial properties have been acquired by metronidazole to the films to be synthesized. The films obtained were coated on glass surface samples by dip coating method.

Chemistry, Structures, and Advanced Applications of Nanocomposites from Biorenewable Resources.

Researchers have recently focused on the advancement of new materials from biorenewable and sustainable sources because of great concerns about the environment, waste accumulation and destruction, and the inevitable depletion of fossil resources. Biorenewable materials have been extensively used as a matrix or reinforcement in many applications. In the development of innovative methods and materials, composites offer important advantages because of their excellent properties such as ease of fabrication, higher mechanical properties, high thermal stability, and many more.

Chitosan/polypropylene glycol hydrogel composite film designed with TiO nanoparticles: A promising scaffold of biomedical applications.

The present study explores the preparation and characterization of chitosan/poly (propylene glycol)/titanium dioxide (CH/PPG/TiO) composite hydrogels in view of their developing applications such as antimicrobial packaging, wound dressing and antibacterial materials. The prepared CH/PPG/TiO films were comprehensively characterized by several methods. The size distribution showed the average size of the TiO nanoparticles (NPs) was about 40 nm.

Assessing short-term effects of magnetite ferrite nanoparticles on Daphnia magna.

Magnetic nanoparticles (MNPs) are used in a wide range of sectors ranging from electronics to biomedicine, as well as in eutrophicated lake restoration due to their high P, N, and heavy metal adsorption capacity. This study assessed the effects of MNPs on mortality and morphometric changes of D. magna.

Recent Progress and Perspectives on Polyurethane Membranes in the Development of Gas Sensors.

In today's technology, gas sensors are of great importance in areas such as assessing environmental impacts, monitoring gas production facilities, measuring natural gas, controlling mines and gas leaks. Improving sensor sensitivity and decreasing the determination time is among the subjects that are continuously investigated. The use of polymeric membranes to make such improvements is common practice in the gas sensor field.

Melatonin protects sperm cells of Capoeta trutta from toxicity of titanium dioxide nanoparticles.

In this study, it was aimed to determine the protective effects of melatonin (0.01, 0.1, and 1 mM) against 10 mg/L titanium dioxide nanoparticles (TiO-NPs) on kinematic and oxidative indices in the sperm cells of Capoeta trutta.

Laccase-conjugated thiolated chitosan-FeO hybrid composite for biocatalytic degradation of organic dyes.

In this study, a novel immobilization support for laccase was developed to enhance enzyme stability, efficiency and reusability. Firstly, FeO magnetic particles were synthesized and modified by the co-precipitation route using thiolated chitosan (TCS). The support was characterized using several methods.

Investigation of toxic effects of amorphous SiO nanoparticles on motility and oxidative stress markers in rainbow trout sperm cells.

In this study, we investigated the effects of SiO nanoparticles (SiO-NPs) (1, 10, 25, 50, and 100 mg/L) for 24 h in vitro on the motility parameters and oxidative stress markers such as total glutathione (TGSH), catalase (CAT), and malondialdehyde (MDA) of rainbow trout, Oncorhynchus mykiss sperm cells. Therefore, SiO-NPs were synthesized with sol-gel reaction from tetraethoxy orthosilicate (TEOS). The prepared nanoparticle structures were characterized for chemical structure, morphology and thermal behavior employing Fourier transform infrared spectroscopy, X-ray spectroscopy, scanning electron micrograph, and thermal analysis (DTA/TGA/DSC) techniques.

Magnetic-propelled FeO-chitosan carriers enhance l-asparaginase catalytic activity: a promising strategy for enzyme immobilization.

Magnetic-propelled carriers comprising magnetic FeO-chitosan nanoparticles were immobilized with l-asparaginase (l-ASNase). The enzyme displayed enhanced catalytic activity in a weak magnetic field, and thermal and pH stabilities. The conjugated l-ASNase presented higher thermostability and wider range of pH stability in comparison with those of free l-ASNase.

The Toxicity Assessment of Iron Oxide (Fe₃O₄) Nanoparticles on Physical and Biochemical Quality of Rainbow Trout Spermatozoon.

The aim of this study was to evaluate the in vitro effect of different doses (50, 100, 200, 400, and 800 mg/L) of Fe₃O₄ nanoparticles (NPs) at 4 °C for 24 h on the kinematics of rainbow trout (, Walbaum, 1792) spermatozoon. Firstly, Fe₃O₄ NPs were prepared at about 30 nm from Iron (III) chloride, Iron (II) chloride, and NH₃ via a co-precipitation synthesis technique. Then, the prepared Fe₃O₄ NPs were characterized by different instrumental techniques for their chemical structure, purity, morphology, surface properties, and thermal behavior.

Chloro-Modified Magnetic FeO@MCM-41 Core-Shell Nanoparticles for L-Asparaginase Immobilization with Improved Catalytic Activity, Reusability, and Storage Stability.

This paper describes a new support that permits to efficient immobilization of L-asparaginase (L-ASNase). For this purpose, FeO magnetic nanoparticles were synthesized and coated by MCM-41. 3-chloropropyltrimethoxysilane (CPTMS) was used as a surface modifying agent for covalent immobilization of L-ASNase on the magnetic nanoparticles.

The in vitro toxicity analysis of titanium dioxide (TiO) nanoparticles on kinematics and biochemical quality of rainbow trout sperm cells.

In recent years, titanium dioxide (TiO) nanoparticles (NPs) as metal oxide nanoparticles are widely used in industry, agriculture, personal care products, cosmetics, sun protection and toothpaste, electronics, foodstuffs and food packaging. This use of nano-TiO has been associated with environmental toxicity concerns. Therefore, the aim of this study was to evaluate the in vitro effect of different doses of TiO NPs (∼30-40 nm) (0.

Magnetic FeO@MCM-41 core-shell nanoparticles functionalized with thiol silane for efficient l-asparaginase immobilization.

l-Asparaginase (l-ASNase) is a vital enzyme for medical treatment and food industry. Here, we assessed the use of FeO@Mobil Composition of Matter No. 41 (MCM-41) magnetic nanoparticles as carrier matrix for l-ASNase immobilization.

Design of epoxy-functionalized FeO@MCM-41 core-shell nanoparticles for enzyme immobilization.

The scope of our research was to prepare the organosilane-modified FeO@MCM-41 core-shell magnetic nanoparticles, used for L-ASNase immobilization and explored screening of immobilization conditions such as pH, temperature, thermal stability, kinetic parameters, reusability and storage stability. In this content, FeO core-shell magnetic nanoparticles were prepared via co-precipitation method and coated with MCM-41. Then, FeO@MCM-41 magnetic nanoparticles were functionalized by (3-glycidyloxypropyl) trimethoxysilane (GPTMS) as an organosilane compound.

Design of starch functionalized biodegradable P(MAA-co-MMA) as carrier matrix for l-asparaginase immobilization.

We prepared biodegradable P(MAA-co-MMA)-starch composite as carrier matrix for the immobilization of l-asparaginase (l-ASNase), an important chemotherapeutic agent in acute lymphoblastic leukemia. Chemical characteristics and thermal stability of the prepared composites were determined by FT-IR, TGA, DTA and, DSC, respectively. Also, biodegradability measurements of P(MAA-co-MMA)-starch composites were carried out to examine the effects of degradation of the starch.